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Monika Fleshner

作者:时间:2019-08-05点击数:

2-Jul-19 1
CURRICULUM VITAE
Monika Fleshner, PhD
I. PERSONAL INFORMATION
Address: 1Department of Integrative Physiology
2The Center for Neuroscience
University of Colorado-Boulder, Campus Box 354
Boulder, CO 80309
Phone: (303) 492-1483
Email: fleshner@colorado.edu
Monika Fleshner, PhD is a professor in the Department of Integrative Physiology, a member of the
Center for Neuroscience, the director of the Stress Physiology laboratory, and the winner of the
international 2019 Norman Cousins Award from the Psychoneuroimmunology Research Society and the
national 2016 Guyton Distinguished Lectureship Award from the Association of
Chairs of Departments of Physiology. She teaches undergraduate and graduate
immunology and has trained ~50 MS/PhD/Postdoctoral students. Her
integrative research program focuses on understanding 1) the impact of acute
and chronic stressor exposure (mental and physical) on behavior, neural,
hormonal and immunological function; 2) how such systems interact to affect
the whole organism; and 3) the mechanisms of increased stress robustness
(resistance/resilience) produced by exercise, prebiotics and cannabis
constituents. She has published ~193 peer-reviewed articles and has a
GoogleScholar h-index of 73. Dr. Fleshner serves on the editorial boards of the
Neurobiology of Stress, Brain, Behavior and Immunity (DAMPs, Special Issue)
and Frontiers in Neuroscience. The National Science Foundation, the National
Institutes of Health, the Department of Defense, and Mead Johnson Nutrition have previously funded
her research program. Current funding is provided by the Office of Naval Research and NASA. Dr.
Fleshner has served as a member of the College of Arts and Sciences Dean’s Budget Committee (2017-
present), the Chair of the Boulder Faculty Assembly (BFA) Budget and Planning Committee (2014-2016),
a member of the BFA Executive Committee (2014-2016), faculty associate for the Vice Chancellor for
Research at the University of Colorado in Boulder (2009-2013), as President of the International Society
for Exercise Immunology (ISEI, 2011-2013), and President (2011-2012) and Secretary/Treasurer (2004-
2006) of the Psychoneuroimmunology Research Society (PNIRS).
II. EDUCATION
1991-1993 Postdoctoral Fellow, Neuroscience
University of Colorado, Boulder, CO
1990-1991 Postdoctoral Fellow, Microbiology/Immunology
University of Colorado Health Science Center, Denver CO
1988-1990 PhD, Behavioral Neuroscience
University of Colorado, Boulder, CO
1986-1988 MA, Behavioral Neuroscience
University of Colorado, Boulder, CO
1982-1984 BS, Psychology
Iowa State University, Ames, IA
2-Jul-19 2
III. PROFESSIONAL ACADEMIC POSITIONS
2009-present Professor with Tenure
Department of Integrative Physiology
University of Colorado at Boulder CO
2003-2008 Associate Professor with Tenure
Department of Integrative Physiology
University of Colorado at Boulder CO
2002-present Faculty
Center for Neuroscience
University of Colorado, Boulder CO
1997-2003 Assistant Professor
Department of Integrative Physiology
University of Colorado, Boulder CO
1996-1997 Assistant Research Professor
Behavioral Neuroscience
University of Colorado, Boulder CO
1993-1996 Research Associate and Instructor
Behavioral Neuroscience
University of Colorado, Boulder CO
1993-1995 Instructor
Department of Psychology
University of Colorado, Denver CO
IV. LEADERSHIP/ADMINISTRATIVE POSITIONS (description of duties in IX. Service)
2018-present Radiation Safety Committee, Vice Chair, University of Colorado at Boulder.
2017-present Executive Committee, Department of Integrative Physiology, University of
Colorado at Boulder.
2014-2016 Boulder Faculty Assembly Executive Committee, University of Colorado at
Boulder.
2014-2016 Boulder Faculty Assembly Budget and Planning Committee, Chair (elected
position), University of Colorado at Boulder.
2009-2013 Faculty Associate
Office of the Vice Chancellor for Research
University of Colorado at Boulder CO
2011-2012 Psychoneuroimmunology Research Society (https://www.pnirs.org/)
President (elected position)
2011-2013 International Society for Exercise Immunology (http://www.isei.dk/)
President (elected position)
2004-2006 Psychoneuroimmunology Research Society
Secretary/Treasurer (elected position)
V. HONORS and AWARDS
2019 Norman Cousins Award, Psychoneuroimmunology Research Society
(International) https://www.pnirs.org/society/society_awards.cfm
2016 Arthur C. Guyton Distinguished Lectureship Award, Association of Chairs of
Departments of Physiology (National)
2-Jul-19 3
2014 Boulder Faculty Assembly Service Recognition Award, University of Colorado,
Boulder
2014 Student Award (Kristina Hulen) Everson Trust Undergraduate Scholarship for
Women in Science
2012-2013 Excellence in Leadership Program, University of Colorado System
2013 Student Award (Parsa Ghasem) Best Poster Presentation @ Rocky Mountain
Regional Neuroscience Group
2010-2013 College of CSR Reviewers, National Institutes of Health
2010 Public Broadcast System (PBS)-The Science of Healing
2009 Boulder Faculty Assembly Award-Excellence in Research
2002 National Public Radio-The Infinite Mind, Featured Scientist
2005 Independent Investigator Award, National Alliance for Research on
Schizophrenia and Depression
2001 Motor Board Honor Society, Faculty Appreciation
1998 Young Investigator Award, Psychoneuroimmunology Research Society
1998 Junior Faculty Development Award, University of Colorado, Boulder CO
1997 Society for Neuroscience CNN (national and international), Featured Scientist
1992-1994 National Institutes of Health
Behavioral Neuroscience Postdoctoral Fellowship
1991 National Institutes of Health
Developmental Psychobiology Postdoctoral Fellowship
1988 Research featured on PBS, "The Mind"
1986-1990 National Institutes of Health Training Grant Fellowship
1984 Phi Kappa Phi
1984 Graduated with Honors, BS, Iowa State University, Ames, IA
1981 Rivercade Queen Undergraduate Scholarship
Morningside College, Sioux City, IA
VI. GRANTS: ACTIVE, PENDING and COMPLETED
i. Active
“The microbiome and responsiveness to stress: Countermeasure Strategies for improving resilience to
sleep and circadian disruption”
Office of Naval Research (ONR) MURI N00014-15-1-2809
Multiple Principle Investigators (MPI), Ken Wright (Team Leader), Monika Fleshner, Chris Lowry, Fred
Turek, Rob Knight, Pieter Dorrestein
Period: 2015-2020
Total Award: $7,100,000. Fleshner Project ($1,400,000)
“A systems-biology approach to assessing the impact of a centrifugation model of spaceflight on crosssystem
communication”
NASA-NSPIRES, 16-ROSBFP_PI-0079
Research Opportunities in Space Biology (ROSBio) - Solicitation of Proposals for Flight and Ground
Space Biology Research
Multiple Principle Investigators, Monika Fleshner (CU), Michael Pecaut (Loma Linda University),
Christopher Wilson (Loma Linda University).
Period: 2019-2021
Total Award: $750,000, Fleshner Subcontract ($275,000)
2-Jul-19 4
ii. Pending
“Gene x Environment Interactions: Does fever trigger spontaneous seizure in the CDKL5 deficient rat
model?”
ORPHAN & Lou Lou Foundation
Principal Investigator, Monika Fleshner; Co-PI, Heidi Grabenstatter
CDKL5 Program of Excellence, Pilot Grant Program
Period: 2019-2020
Total Award: $150,000
“Cell-Derived Microparticles in Hypertension: Biomarkers, Vascular Mediators, and Therapeutic
Targets”
NIH-HL-16-024, Multiple Principle Investigators, DeSouza, Fleshner, Link, Stauffer, McQueen
Period: 2019-2021
Total Award: $1,200,000
“Prediabetes, Exercise, and Microparticles”
NIH, Multiple Principle Investigators, DeSouza, Fleshner, Stauffer
Period: 2019-2022
Total Award: $1,150,000
“Gravity & Increased Diabetic Risk: Links with Immuno-metabolism and Microbiome.”
NASA, NNH18ZTT001N-FG, Multiple Principle Investigators, Pecaut, Fleshner, Jonscher, Blaber
Period: 2019-2021
Total Award: 1,145,000, Fleshner Subcontract: $270,000
iii. Completed
“Nutritional Modulation of Brain Development, Cognitive Function, Sleep, and Stress Reactivity: The
Role of the Gut Microbiota”
Mead Johnson Nutrition, Principle Investigator, Monika Fleshner
Period: 2013-2017
Total Award: $1,055,749
“Neurobiology of the Stress Resistant Brain”
R01-MH068283-06, NIH, Principal Investigator, Monika Fleshner
Period: 2010-2015
Total Award: $1,200,000
“Extracellular Hsp72 is a DAMP Released by Stress”
IOS 1022451 NSF, Principal Investigator, Monika Fleshner
Period: 2010-2013
Total Award: $539,045
“Enabling Stress Resistance with Controllable Exercise”
DARPA, W911NF-10-1-0050. Defense Science Office, Principal Investigator
Period: 2010-2012
Total Award: $2,800,000
2-Jul-19 5
“Preventing Transition of Acute-to-Chronic Neuropathic Pain: Models, Mechanisms, and Treatment”
RO1-DE021966, NIH, Multiple Principle Investigators (MPI) PD/PI, Linda Watkins, Monika Fleshner,
Dan Barth
Period: 2011-2016
Total Award: $1,800,000
“Exercise Mitigates Stress-Induced Memory Disturbances”
RO3-NIMH, NIH, Co-PI, Monika Fleshner
Period: 2009-2012
Total Award: $143,000
“Physiological Functions of the Gut Microbiome”
Innovative Seed Grant Program-U of CO, Principal Investigator, Monika Fleshner
Period: 2010-2012
Total Award: $43,750
“Stress, Heat-Shock Proteins and Innate Immunity”
R01-AI057797-01, NIH, Principal Investigator, Monika Fleshner
Period: 2004-2010
Total Award: $1,738,025
“Chemotherapy and Cognition in Older Breast Cancer Patients”
(SUBCONTRACT) NIH, Principal Investigator, Monika Fleshner
Period: 2004-2009
Total Award: $154,000
“The Neurobiology of the Stress Resistant Brain”
R01-MH068283-01, NIH, Principal Investigator, Monika Fleshner
Period: 2004-2009
Total Award: $1,804,225
“Prevention of the Negative Behavioral Effects of Acute Fluoxetine: Role of BDNF”
NARSAD, Principal Investigator, Monika Fleshner
Period: 2005-2009
Total Award: $100,000
“Regulation of Brain IL-1 and Sickness Responses Following E.coli Challenge”
R21-MH NIH, Co-Investigator, Monika Fleshner
Period: 2007-2009
Total Award: $403,820
Leap Associate Professor Award
University of Colorado, Principal investigator, Monika Fleshner
Period: 2004-2005
Total Award: $5,000
“Stress, Exercise, and Innate Immunity”
RO3-MH60301-01, NIH, Principal Investigator, Monika Fleshner
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Period: 1999-2001
Total Award: $35,875
“Exercise Prevents the Immunosuppressive Effect of Stress”
RO3-AI45576-01, NIH, Principal Investigator, Monika Fleshner
Period: 1999-2001
Total Award: $143,131
"Exercise, Stress and Immunity: Physiological Mechanisms"
RO1-AI48555-01, NIH, Principal Investigator, Monika Fleshner
Period: 2000-2004
Total Award: $1,223,472
“Exercise and Stress Resistance: A Systems Biology Approach”
CRCW, University of Colorado, Principal Investigator, Monika Fleshner
Period: 2006-2007
Total Award: $7,000
“Obesity/Insulin Resistance and Endothelial t-PA Release”
RO3-DK62061, NIH, Co-Investigator, Monika Fleshner
Period: 2002-2004
Total Award: $143,131
“Arousal and Motor Performance in Older Adults”
RO3-AG20339, NIH, Co-Investigator, Monika Fleshner
Period: 2002-2004
Total Award: $143,000
“Effect of Sleep Deprivation on Inflammatory Markers”
NIH, Co-Investigator, Monika Fleshner
Period: 2002-2004
Total Award: $290,369
“Potential Benefits of a Physically Active Lifestyle on Immune Response to Immunization"
protocol B5009, General Clinical Research Center-Boulder Satellite, NIH, Principal Investigator, Monika
Fleshner
Period: 2000-2002
Total Award: $15,000
“Neural Mechanisms of the Stress-Resistant Brain”
University of Colorado, Council on Creative Work, Principal Investigator, Monika Fleshner
Period: 2002
Total Award: $2,500
“The Behavioral Analysis of the Protective Effect of Exercise” Council on Research and Creative Work”
University of Colorado, Principal Investigator, Monika Fleshner
Period: 1999-2000
Total Award: $6,730
2-Jul-19 7
Junior Faculty Development Award, University of Colorado
Principal Investigator, Monika Fleshner
Period: 1998
Total Award: $5,000
"Stress and Immunity: Behavioral and Physiological Mechanisms
RO1-MH-4505, NIH, Co-Investigator, Monika Fleshner
Period: 1996-2001
Total Award: $1,725,994
“Effects of space flight on in vivo immune function and bone resorption”
BioServe-NASA (SUBCONTRACT), Principal Investigator, Monika Fleshner
Period: 1996
Total Award: $3,500
University of Colorado Health Sciences Center Young Investigator Award
Principal Investigator, Monika Fleshner
Period: 1991-1992
Total Award: $3,000
VII. PUBLICATIONS
GoogleScholar
Total Citations (09.13.18): 17,900
h-index: 73
10-index: 173
i. Manuscripts / Chapters Submitted (Peer-reviewed)
*indicates 1st author is/was a student or postdoctoral fellow supervised by Dr. Fleshner
Fleshner, M. Gut-Microbial Signaling: A New Player in Stress Physiology? European Journal of
Neuroscience (2019) Invited Commentary (in review).
Thompson, RS*; Vargas, F; Dorrestein, PC; Chichlowski, M; Berg, BM; Fleshner, M.
The fecal metabolome is atered by stress and dietary prebiotics: Relationships between
metabolomic features, sleep architecture, and microbiome alpha diversity. Metabolomics (2019) in
review.
Bowers, SJ; Vargas, F; González, A; Hea, S; Dorrestein, PC; Knight, R; Wright Jr, KP; Lowry, CA; Fleshner,
M; Vitaterna, MH; Turek, FW. Repeated sleep disruption in mice leads to shifts in the fecal
microbiome and metabolome that persist multiple days into recovery sleep. Microbiome (2019) in
review.
Bowers, SJ*; Thompson, RS; Mika, A, Greenwood, BN; Fleshner, M. Disruption of the gut microbiome
with oral antibiotic reduces core body temperature and disrupts diurnal rhythms of locomotor
activity, but not sleep, in adult rats, in prep.
2-Jul-19 8
ii. Manuscript/Chapters Published or In Press (Peer-Reviewed)
*indicates 1st author is/was a student or postdoctoral fellow supervised by Dr. Fleshner
Arnold, MR; Greenwood, BN; McArthur, JA; Clark, PJ; Fleshner, M; Lowry, CA. Effect of repeated
voluntary or forced exercise on brainstem serotonergic systems in rats. Behavioral Brain Research
(2019) in press.
Sprecher, K; Ritchie, H; Burke, T; Depner, C; Smits, A; Dorrestein, P; Fleshner, M; Knight, R; Lowry, C;
Turek, F; Vitaterna, M; Wright, K. Trait-like vulnerability of higher-order cognition and ability to
maintain wakefulness during combined sleep restriction and circadian misalignment. Sleep (2019)
in press.
Greenwood, BN; Fleshner, M. Voluntary wheel running: A useful rodent model for Investigating the
mechanisms of stress robustness and neural circuits of exercise motivation. Current Opinion in
Behavioral Sciences (2019) in press.
Mika, A*; Gaffney, M; Roller, R; Hills, A; Bouchet, CA; Hulen, KA; Thompson, RS; Chichlowski, M; Berg,
BM; Fleshner, M. Feeding the Developing Brain: Juvenile Rats Fed Diet Rich in Prebiotics and
Bioactive Milk Fractions Exhibit Reduced Anxiety-Related Behavior and Modified Gene Expression in
Emotion Circuits. Neurosci Lett, (2018) 677: p. 103-109.10.1016/j.neulet.2018.01.052.
Fleshner, M. and Crane, CR*. Exosomes, DAMPs and miRNA: Features of stress physiology and immune
homeostasis. Trends in Immunology, (2017) 38 p. 63 doi: 10.1016/j.it.2017.08.002.
Thompson, RS*; Roller, R; Greenwood, BN; Knight, R; Chichlowski, M; Berg, BM; Fleshner, M. Dietary
prebiotics and bioactive milk fractions support early-life NREM sleep quality, REM rebound sleep
recovery following acute stress and ameliorate stress-induced decrease in alpha diversity in the rat.
Frontiers in Behavioral Neuroscience, (2017) 10, 10:240. doi: 10.3389/fnbeh.2016.00240.
Lloyd, BA; Hake, HS; Ishiwata, T; Farmer, CE; Loetz, EC; Fleshner, M; Bland, ST; Greenwood, BN. Exercise
Increases mTor Signaling in Brain Regions Involved in Cognition and Emotional Behavior. Behav
Brain Res, (2017) 323: p. 56-67.10.1016/j.bbr.2017.01.033.
Fleshner, M; Frank, M; Maier, SF. Danger Signals and Inflammasomes: Stress-Evoked Sterile
Inflammation in Mood Disorders. Neuropsychopharmacology, (2017) 42(1): p. 36-
45.10.1038/npp.2016.125.
Mika, A*; Day, HE; Martinez, A; Rumian, NL; Greenwood, BN; Chichlowski, M; Berg, BM; Fleshner, M.
Early Life Diets with Prebiotics and Bioactive Milk Fractions Attenuate the Impact of Stress on
Learned Helplessness Behaviours and Alter Gene Expression within Neural Circuits Important for
Stress Resistance. Eur J Neurosci, (2017) 45(3): p. 342-357.10.1111/ejn.13444.
Mika, A; Rumian, N; Loughridge, AB; Fleshner, M. Exercise and Prebiotics Produce Stress Resistance:
Converging Impacts on Stress-Protective and Butyrate-Producing Gut Bacteria. Int Rev Neurobiol,
(2016) 131: p. 165-191.10.1016/bs.irn.2016.08.004.
2-Jul-19 9
Speaker, KJ*; Paton, MM; Cox, SS; Fleshner, M. A Single Bout of Fasting (24 H) Reduces Basal Cytokine
Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of
Normal Weight F344 Rats. Mediators Inflamm, (2016) 2016: p. 1698071.10.1155/2016/1698071.
Reber, SO; Siebler, PH; Donner, NC; Morton, JT; Smith, DG; Kopelman, JM; Lowe, KR; Campbell, K; Fox,
JH; Hassell, JE; Greenwood, BN; Jansch, C; Lechner, A; Uschold-Schmidt, N; Füchsl, AM; Langgartner,
D; Walker, FR; Hale, MW; Perez, GL; Van Treuren, W; González, A; Halweg-Edwards, AL; Fleshner,
M. Raison, CL; Rook, GAW; Peddada, SD; Knight, R; Lowry, CA. Immunization with a heat-killed
preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in
mice. Proc Natl Acad Sci U S A, (2016). 113(22): p. E3130-9PMC4896712.
Grace, PM; Fabisiak, TJ; Green-Fulgham, SM; Anderson, ND; Strand, KA; Kwilasz, AJ; Galer, EL; Walker,
FR; Greenwood, BN; Maier, SF; Fleshner, M; Watkins, LR. Prior Voluntary Wheel Running
Attenuates Neuropathic Pain. Pain, (2016) 157(9): p. 2012-23.10.1097/j.pain.0000000000000607.
Thompson, RS*; Roller, R; Greenwood, BN; Fleshner, M. Voluntary exercise increases core body
temperature, improves sleep and reduces the stress-induced flattening of the diurnal rhythms in
temperature and sleep. Stress (2016) 1-13, doi: 10.1080/10253890.2016.1174852.
Mika, A.* and Fleshner, M., Early-life exercise may promote lasting brain and metabolic health through
gut bacterial metabolites. Immunol Cell Biol, (2016). 94(2): p. 151-7 doi:10.1038/icb.2015.113.
Seetharaman, S; Fleshner, M; Park, CR; Diamond, DM. Influence of Daily Social Stimulation on
Behavioral and Physiological Outcomes in an Animal Model of PTSD. Brain Behav, (2016) 6(5): p.
e00458PMC4834360.
Thompson, RS; Roller, R; Greenwood, BN; Fleshner, M. Wheel Running Improves REM Sleep and
Attenuates Stress-Induced Flattening of Diurnal Rhythms in F344 Rats. Stress, (2016) 19(3): p. 312-
24.10.1080/10253890.2016.1174852.
Herrera, JJ*; Fedynska, S; Ghasem, PR; Wieman, T; Clark, PJ; Gray, N; Loetz, E; Campeau, S; Fleshner, M;
Greenwood, BN. Neurochemical and Behavioural Indices of Exercise Reward Are Independent of
Exercise Controllability. Eur J Neurosci, (2016) 43(9): p. 1190-202.10.1111/ejn.13193.
Mika, A*; Bouchet, CA; Bunker, P; Hellwinkel, JE; Spence, KG; Day, HE; Campeau, S; Fleshner, M;
Greenwood, BN. Voluntary Exercise During Extinction of Auditory Fear Conditioning Reduces the
Relapse of Fear Associated with Potentiated Activity of Striatal Direct Pathway Neurons. Neurobiol
Learn Mem, (2015) 125: p. 224-35.10.1016/j.nlm.2015.10.001.
Mika, A*; Van Treuren, W; Gonzalez, A; Herrera, JJ; Knight, R; Fleshner, M. Exercise Is More Effective at
Altering Gut Microbial Composition and Producing Stable Changes in Lean Mass in Juvenile Versus
Adult Male F344 Rats. PLoS One, (2015) 10(5): p. e0125889.10.1371/journal.pone.0125889.
Clark, PJ*; Amat, J; McConnell, SO; Ghasem, PR; Greenwood, BN; Maier, SF; Fleshner, M. Running
Reduces Uncontrollable Stress-Evoked Serotonin and Potentiates Stress-Evoked Dopamine
Concentrations in the Rat Dorsal Striatum. PLoS One, (2015) 10(11): p.
e0141898.10.1371/journal.pone.0141898.
2-Jul-19 10
Wright, KP, Jr.; Drake, AL; Frey, DJ; Fleshner, M; Desouza, CA; Gronfier, C; Czeisler, CA. Influence of
Sleep Deprivation and Circadian Misalignment on Cortisol, Inflammatory Markers, and Cytokine
Balance. Brain Behav Immun, (2015) 47: p. 24-34.10.1016/j.bbi.2015.01.004.
Zoldaz, PR; Park, CR; Fleshner, M; Diamond, DM. Psychosocial predator-based animal of PTSD produces
physiological and behavioral sequellae and traumatic memory four months following stress onset.
Physiology and Behavior, 147 (2015) 183-192. 10.1016/j.physbeh.2015.04.032.
Beninson, L.A.* and Fleshner, M., Exosomes in Fetal Bovine Serum Dampen Primary Macrophage Il-
1beta Response to Lipopolysaccharide (LPS) Challenge. Immunol Lett, (2015) 163(2): p. 187-
92.10.1016/j.imlet.2014.10.019.
Greenwood, BN*; Thompson, RS; Opp, MR; Fleshner, M. Repeated Exposure to Conditioned Fear Stress
Increases Anxiety and Delays Sleep Recovery Following Exposure to an Acute Traumatic Stressor.
Front Psychiatry, (2014) 5: p. 146.10.3389/fpsyt.2014.00146.
van Praag, H; Fleshner, M; Schwartz, MW; Mattson, MP. Exercise, Energy Intake, Glucose Homeostasis,
and the Brain. J Neurosci, (2014) 34(46): p. 15139-49.10.1523/JNEUROSCI.2814-14.2014.
Thompson, RS*; Strong, PV; Clark, PJ; Maslanik, TM; Wright, KP, Jr.; Greenwood, BN; Fleshner, M.
Repeated Fear-Induced Diurnal Rhythm Disruptions Predict PTSD-Like Sensitized Physiological Acute
Stress Responses in F344 Rats. Acta Physiol (Oxf), (2014) 211(2): p. 447-65.10.1111/apha.12239.
Clark, PJ*; Ghasem, PR; Mika, A; Day, HE; Herrera, JJ; Greenwood, BN; Fleshner, M. Wheel Running
Alters Patterns of Uncontrollable Stress-Induced Cfos mRNA Expression in Rat Dorsal Striatum Direct
and Indirect Pathways: A Possible Role for Plasticity in Adenosine Receptors. Behav Brain Res, (2014)
272: p. 252-63.10.1016/j.bbr.2014.07.006.
Fleshner, M; Greenwood, BN; Yirmiya, R. Neuronal-glial mechanisms of exercise-evoked stress
robustness. In Springer Current Topics in Behavioral Neuroscience, Behavioral Neurobiology of
Stress-related Disorders, ed., M.D. Lapiz Bluhm and C. Pariante. (2014) 10.1007/7854_2014_277.
Beninson, L.A.* and Fleshner, M., Exosomes: An Emerging Factor in Stress-Induced Immunomodulation.
Semin Immunol, (2014) 26(5): p. 394-401.10.1016/j.smim.2013.12.001.
Beninson, LA*; Brown, PN; Loughridge, AB; Saludes, JP; Maslanik, T; Hills, AK; Woodworth, T; Craig, W;
Yin, H; Fleshner, M. Acute Stressor Exposure Modifies Plasma Exosome-Associated Heat Shock
Protein 72 (Hsp72) and MicroRNA (Mir-142-5p and Mir-203). PLoS One, (2014) 9(9): p.
e108748.10.1371/journal.pone.0108748.
Cox, SS*; Speaker, KJ; Beninson, LA; Craig, WC; Paton, MM; Fleshner, M. Adrenergic and Glucocorticoid
Modulation of the Sterile Inflammatory Response. Brain Behav Immun, (2014) 36: p. 183-
92.10.1016/j.bbi.2013.11.018.
Speaker, KJ*; Cox, SS; Paton, MM; Serebrakian, A; Maslanik, T; Greenwood, BN; Fleshner, M. Six Weeks
of Voluntary Wheel Running Modulates Inflammatory Protein (MCP-1, IL-6, and IL-10) and Damp
(Hsp72) Responses to Acute Stress in White Adipose Tissue of Lean Rats. Brain Behav Immun, (2014)
39: p. 87-98.10.1016/j.bbi.2013.10.028.
2-Jul-19 11
Saludes, JP; Morton, LA; Coulup, SK; Fiorini, Z; Cook, BM; Beninson, L; Chapman, ER; Fleshner, M; Yin, H.
Multivalency Amplifies the Selection and Affinity of Bradykinin-Derived Peptides for Lipid
Nanovesicles. Mol Biosyst, (2013) 9(8): p. 2005-9.10.1039/c3mb70109c.
Loughridge, AB*; Greenwood, BN; Day, HE; McQueen, MB; Fleshner, M. Microarray Analyses Reveal
Novel Targets of Exercise-Induced Stress Resistance in the Dorsal Raphe Nucleus. Front Behav
Neurosci, (2013) 7: p. 37.10.3389/fnbeh.2013.00037.
Thompson, RS*; Christianson, JP; Maslanik, TM; Maier, SF; Greenwood, BN; Fleshner, M. Effects of
Stressor Controllability on Diurnal Physiological Rhythms. Physiol Behav, (2013) 112-113: p. 32-
9.10.1016/j.physbeh.2013.02.009.
Zoladz, PR; Fleshner, M; Diamond, DM. Differential Effectiveness of Tianeptine, Clonidine and
Amitriptyline in Blocking Traumatic Memory Expression, Anxiety and Hypertension in an Animal
Model of PTSD. Prog Neuropsychopharmacol Biol Psychiatry, (2013) 44: p. 1-
16.10.1016/j.pnpbp.2013.01.001.
Greenwood, BM*; Fleshner, M. Mechanisms underlying the relationship between physical activity and
anxiety: Animal data. In Routledge Handbook of Physical Activity and Mental Health (2013) pp 130-
142.
Fleshner, M. Thompson, RS; Greenwood, BN. Impact of physical activity on diurnal rhythms: A potential
mechanism for exercise-induced stress resistance and stress resilience. In Routledge Handbook of
Physical Activity and Mental Health (2013) pp 316-328.
Morton, LA; Yang, H; Saludes, JP; Fiorini, Z; Beninson, L; Chapman, ER; Fleshner, M; Xue, D; Yin, H.
Marcks-Ed Peptide as a Curvature and Lipid Sensor. ACS Chem Biol, (2013) 8(1): p. 218-
25.10.1021/cb300429e.
Fleshner, M. Stress-Evoked Sterile Inflammation, Danger Associated Molecular Patterns (Damps),
Microbial Associated Molecular Patterns (MAMPs) and the Inflammasome. Brain Behav Immun,
(2013) 27(1): p. 1-7.10.1016/j.bbi.2012.08.012.
Maslanik, T*; Mahaffey, L; Tannura, K; Beninson, L; Greenwood, BN; Fleshner, M. The Inflammasome
and Danger Associated Molecular Patterns (DAMPs) Are Implicated in Cytokine and Chemokine
Responses Following Stressor Exposure. Brain Behav Immun, (2013) 28: p. 54-
62.10.1016/j.bbi.2012.10.014.
Greenwood, BN*; Spence, KG; Crevling, DM; Clark, PJ; Craig, WC; Fleshner, M. Exercise-Induced Stress
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for Nitric Oxide. Physiol Behav, (2002) 77(2-3): p. 291-9,
https://www.ncbi.nlm.nih.gov/pubmed/12419405.
Fleshner, M; Campisi, J; Deak, T; Greenwood, BN; Kintzel, JA; Leem, TH; Smith, TP; Sorensen, B. Acute
Stressor Exposure Facilitates Innate Immunity More in Physically Active Than in Sedentary Rats. Am
J Physiol Regul Integr Comp Physiol, (2002) 282(6): p. R1680-6.10.1152/ajpregu.00661.2001.
Moraska, A*; Campisi, J; Nguyen, KT; Maier, SF; Watkins, LR; Fleshner, M. Elevated Il-1beta Contributes
to Antibody Suppression Produced by Stress. J Appl Physiol (1985), (2002) 93(1): p. 207-
15.10.1152/japplphysiol.01151.2001.
Pugh, CR; Fleshner, M. Watkins, LR; Maier SF; Rudy, JW; Converging evidence for an adverse effect of
interleukin-1beta on learning and memory. Neuroscience and Biobehavioral Reviews, 25 (2001) 29-
41.
Fleshner, M; Deak, T; Nguyen, KT; Watkins, LR; Maier, SF. Endogenous Glucocorticoids Play a Positive
Regulatory Role in the Anti-Keyhole Limpet Hemocyanin in Vivo Antibody Response. J Immunol,
(2001) 166(6): p. 3813-9, https://www.ncbi.nlm.nih.gov/pubmed/11238624.
Noteboom, JT; Fleshner, M; Enoka, RM. Activation of the Arousal Response Can Impair Performance on
a Simple Motor Task. J Appl Physiol (1985), (2001) 91(2): p. 821-31.10.1152/jappl.2001.91.2.821.
Moraska, A.* and Fleshner, M., Voluntary Physical Activity Prevents Stress-Induced Behavioral
Depression and Anti-Klh Antibody Suppression. Am J Physiol Regul Integr Comp Physiol, (2001)
281(2): p. R484-9.10.1152/ajpregu.2001.281.2.R484.
Pugh, CR; Fleshner, M; Watkins, LR; Maier, SF; Rudy, JW. The Immune System and Memory
Consolidation: A Role for the Cytokine Il-1beta. Neurosci Biobehav Rev, (2001) 25(1): p. 29-41,
https://www.ncbi.nlm.nih.gov/pubmed/11166076.
Fleshner, M. The immunity of the brain: the role of brain cytokines in physiology and pathophysiology.
Psychosomatic Medicine, (2001) 63, 511-515.
Mazzeo, RS; Donovan, D; Fleshner, M; Butterfield, GE; Zamudio, S; Wolfel, EE; Moore, LG. Interleukin-6
Response to Exercise and High-Altitude Exposure: Influence of Alpha-Adrenergic Blockade. J Appl
Physiol (1985), (2001) 91(5): p. 2143-9.10.1152/jappl.2001.91.5.2143.
Moraska, A*; Deak, T; Spencer, RL; Roth, D; Fleshner, M. Treadmill Running Produces Both Positive and
Negative Physiological Adaptations in Sprague-Dawley Rats. Am J Physiol Regul Integr Comp
Physiol, (2000) 279(4): p. R1321-9.10.1152/ajpregu.2000.279.4.R1321.
Hansen, MK; Nguyen, KT; Fleshner, M; Goehler, LE; Gaykema, RP; Maier, SF; Watkins, LR. Effects of
Vagotomy on Serum Endotoxin, Cytokines, and Corticosterone after Intraperitoneal
Lipopolysaccharide. Am J Physiol Regul Integr Comp Physiol, (2000) 278(2): p. R331-
6.10.1152/ajpregu.2000.278.2.R331.
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Fleshner, M. Exercise and Neuroendocrine Regulation of Antibody Production: Protective Effect of
Physical Activity on Stress-Induced Suppression of the Specific Antibody Response. Int J Sports Med,
(2000) 21 Suppl 1: p. S14-9, https://www.ncbi.nlm.nih.gov/pubmed/10893019.
Nguyen, KT; Deak, T; Will, MJ; Hansen, MK; Hunsaker, BN; Fleshner, M; Watkins, LR; Maier, SF.
Timecourse and Corticosterone Sensitivity of the Brain, Pituitary, and Serum Interleukin-1beta
Protein Response to Acute Stress. Brain Res, (2000) 859(2): p. 193-201,
https://www.ncbi.nlm.nih.gov/pubmed/10719064.
Pecaut, MJ*; Simske, SJ; Fleshner, M. Spaceflight Induces Changes in Splenocyte Subpopulations:
Effectiveness of Ground-Based Models. Am J Physiol Regul Integr Comp Physiol, (2000) 279(6): p.
R2072-8.10.1152/ajpregu.2000.279.6.R2072.
Hansen, MK; Nguyen, KT; Goehler, LE; Gaykema, RP; Fleshner, M; Maier, SF; Watkins, LR. Effects of
Vagotomy on Lipopolysaccharide-Induced Brain Interleukin-1beta Protein in Rats. Auton Neurosci,
(2000) 85(1-3): p. 119-26, https://www.ncbi.nlm.nih.gov/pubmed/11189018.
Colagiovanni, DB; Suniga, MA; Frazier, JL; Edwards, CK, 3rd; Fleshner, M; McCay, JA; White, KL, Jr.;
Shopp, GM. Tnf-Alpha Blockade by a Dimeric Tnf Type I Receptor Molecule Selectively Inhibits
Adaptive Immune Responses. Immunopharmacol Immunotoxicol, (2000) 22(4): p. 627-
51.10.3109/08923970009016429.
Deak, T; Nguyen, KT; Fleshner, M; Watkins, LR; Maier, SF. Acute Stress May Facilitate Recovery from a
Subcutaneous Bacterial Challenge. Neuroimmunomodulation, (1999) 6(5): p. 344-
54.10.1159/000026394.
Noble, EG; Moraska, A; Mazzeo, RS; Roth, DA; Olsson, MC; Moore, RL; Fleshner, M. Differential
Expression of Stress Proteins in Rat Myocardium after Free Wheel or Treadmill Run Training. J Appl
Physiol (1985), (1999) 86(5): p. 1696-701.10.1152/jappl.1999.86.5.1696.
Mesches, MH; Fleshner, M; Heman, KL; Rose, GM; Diamond, DM. Exposing Rats to a Predator Blocks
Primed Burst Potentiation in the Hippocampus in Vitro. J Neurosci, (1999) 19(14): p. RC18,
https://www.ncbi.nlm.nih.gov/pubmed/10407060.
Diamond, DM; Fleshner, M. Constraints on the DHEAS-induced enhancement of hippocampal function:
Non-Linear dose response functions and DHEAS-stress interactions. In: The Biological Role of
Dehydroepiandrosterone (DHEA) and Pregnenolone, Volume II, Walter de Gruyer, Berlin, (1999)
261-270.
Pugh, CR; Nguyen, KT; Gonyea, JL; Fleshner, M; Wakins, LR; Maier, SF; Rudy, JW. Role of Interleukin-1
Beta in Impairment of Contextual Fear Conditioning Caused by Social Isolation. Behav Brain Res,
(1999) 106(1-2): p. 109-18, https://www.ncbi.nlm.nih.gov/pubmed/10595426.
Todd, P; Pecaut, MJ; Fleshner, M. Combined Effects of Space Flight Factors and Radiation on Humans.
Mutat Res, (1999) 430(2): p. 211-9, https://www.ncbi.nlm.nih.gov/pubmed/10631335.
Diamond, DM; Fleshner, M; Rose, GM. The Enhancement of Hippocampal Primed Burst Potentiation by
Dehydroepiandrosterone Sulfate (Dheas) Is Blocked by Psychological Stress. Stress, (1999) 3(2): p.
2-Jul-19 21
107-21, https://www.ncbi.nlm.nih.gov/pubmed/10938573.
Deak, T; Nguyen, KT; Cotter, CS; Fleshner, M; Watkins, LR; Maier, SF; Spencer, RL. Long-Term Changes in
Mineralocorticoid and Glucocorticoid Receptor Occupancy Following Exposure to an Acute Stressor.
Brain Res, (1999) 847(2): p. 211-20, https://www.ncbi.nlm.nih.gov/pubmed/10575090.
Nguyen, KT; Deak, T; Owens, SM; Kohno, T; Fleshner, M; Watkins, LR; Maier, SF. Exposure to Acute
Stress Induces Brain Interleukin-1beta Protein in the Rat. J Neurosci, (1998) 18(6): p. 2239-46,
https://www.ncbi.nlm.nih.gov/pubmed/9482808.
Maier, SF; Goehler, LE; Fleshner, M; Watkins, LR. The Role of the Vagus Nerve in Cytokine-to-Brain
Communication. Ann N Y Acad Sci, (1998) 840: p. 289-300,
https://www.ncbi.nlm.nih.gov/pubmed/9629257.
Fleshner, M; Goehler, LE; Schwartz, BA; McGorry, M; Martin, D; Maier, SF; Watkins, LR. Thermogenic
and Corticosterone Responses to Intravenous Cytokines (Il-1beta and Tnf-Alpha) Are Attenuated by
Subdiaphragmatic Vagotomy. J Neuroimmunol, (1998) 86(2): p. 134-41,
https://www.ncbi.nlm.nih.gov/pubmed/9663558.
Fleshner, M; Nguyen, KT; Cotter, CS; Watkins, LR; Maier, SF. Acute Stressor Exposure Both Suppresses
Acquired Immunity and Potentiates Innate Immunity. Am J Physiol, (1998) 275(3 Pt 2): p. R870-8,
https://www.ncbi.nlm.nih.gov/pubmed/9728086.
Gaykema, RP; Goehler, LE; Tilders, FJ; Bol, JG; McGorry, M; Fleshner, M; Maier, SF; Watkins, LR.
Bacterial Endotoxin Induces Fos Immunoreactivity in Primary Afferent Neurons of the Vagus Nerve.
Neuroimmunomodulation, (1998) 5(5): p. 234-40.10.1159/000026343.
Maier, SF; Fleshner, M. Watkins, LR; Neural, Endocrine and Immune Mechanisms of Stress-induced
immunomodulation. New Frontiers in Stress Research: Modulation of Brain Function, Harwood
Academic Publishers, (1998) 75-186.
Diamond, DM; Ingersoll, N; Branch, BJ; Mesches, MH; Coleman-Mesches, K; Fleshner, M. Stress impairs
cognitive and electrophysiological measures of hippocampal function, In: New Frontiers in Stress
Research: Modulation of Brain Function, Harwood Academic Publishers, (1998), 117-126.
Milligan, ED; Nguyen, KT; Deak, T; Hinde, JL; Fleshner, M; Watkins, LR; Maier, SF. The Long Term Acute
Phase-Like Responses That Follow Acute Stressor Exposure Are Blocked by Alpha-Melanocyte
Stimulating Hormone. Brain Res, (1998) 810(1-2): p. 48-58,
https://www.ncbi.nlm.nih.gov/pubmed/9813238.
Pugh, CR; Kumagawa, K; Fleshner, M; Watkins, LR; Maier, SF; Rudy, JW. Selective Effects of Peripheral
Lipopolysaccharide Administration on Contextual and Auditory-Cue Fear Conditioning. Brain Behav
Immun, (1998) 12(3): p. 212-29.10.1006/brbi.1998.0524.
Pugh, CR; Fleshner, M; Rudy, JW. Type Ii Glucocorticoid Receptor Antagonists Impair Contextual but Not
Auditory-Cue Fear Conditioning in Juvenile Rats. Neurobiol Learn Mem, (1997) 67(1): p. 75-
9.10.1006/nlme.1996.3741.
2-Jul-19 22
Fleshner, M; Pugh, CR; Tremblay, D; Rudy, JW. Dhea-S Selectively Impairs Contextual-Fear Conditioning:
Support for the Antiglucocorticoid Hypothesis. Behav Neurosci, (1997) 111(3): p. 512-7,
https://www.ncbi.nlm.nih.gov/pubmed/9189266.
Pugh, CR; Tremblay, D; Fleshner, M; Rudy, JW. A Selective Role for Corticosterone in Contextual-Fear
Conditioning. Behav Neurosci, (1997) 111(3): p. 503-11,
https://www.ncbi.nlm.nih.gov/pubmed/9189265.
Milligan, ED; McGorry, MM; Fleshner, M; Gaykema, RP; Goehler, LE; Watkins, LR; Maier, SF.
Subdiaphragmatic Vagotomy Does Not Prevent Fever Following Intracerebroventricular
Prostaglandin E2: Further Evidence for the Importance of Vagal Afferents in Immune-to-Brain
Communication. Brain Res, (1997) 766(1-2): p. 240-3,
https://www.ncbi.nlm.nih.gov/pubmed/9359608.
Fleshner, M; Silbert, L; Deak, T; Goehler, LE; Martin, D; Watkins, LR; Maier, SF. Tnf-Alpha-Induced
Corticosterone Elevation but Not Serum Protein or Corticosteroid Binding Globulin Reduction Is
Vagally Mediated. Brain Res Bull, (1997) 44(6): p. 701-6,
https://www.ncbi.nlm.nih.gov/pubmed/9421133.
Deak, T; Meriwether, JL; Fleshner, M; Spencer, RL; Abouhamze, A; Moldawer, LL; Grahn, RE; Watkins,
LR; Maier, SF. Evidence That Brief Stress May Induce the Acute Phase Response in Rats. Am J
Physiol, (1997) 273(6 Pt 2): p. R1998-2004, https://www.ncbi.nlm.nih.gov/pubmed/9435654.
Brennan, FX, Jr.; Fleshner, M; Watkins, LR; Maier, SF. Macrophage Stimulation Reduces the Cholesterol
Levels of Stressed and Unstressed Rats. Life Sci, (1996) 58(20): p. 1771-6,
https://www.ncbi.nlm.nih.gov/pubmed/8637401.
Fleshner, M; Brennan, FX; Nguyen, K; Watkins, LR; Maier, SF. Ru-486 Blocks Differentially Suppressive
Effect of Stress on in Vivo Anti-Klh Immunoglobulin Response. Am J Physiol, (1996) 271(5 Pt 2): p.
R1344-52.10.1152/ajpregu.1996.271.5.R1344.
Lockwood, LL; Silbert, LH; Fleshner, M; McNeal, C; Watkins, LR; Laudenslager, ML; Rice, KC; Weber, RJ;
Maier, SF. Morphine-Induced Alterations in Antibody Levels: Receptor and Immune Mechanisms. J
Pharmacol Exp Ther, (1996) 278(2): p. 689-96, https://www.ncbi.nlm.nih.gov/pubmed/8768720.
Diamond, DM; Branch, BJ; Fleshner, M. The Neurosteroid Dehydroepiandrosterone Sulfate (Dheas)
Enhances Hippocampal Primed Burst, but Not Long-Term, Potentiation. Neurosci Lett, (1996)
202(3): p. 204-8, https://www.ncbi.nlm.nih.gov/pubmed/8848267.
Bennett, MC; Mlady, GW; Fleshner, M; Rose, GM. Synergy between Chronic Corticosterone and Sodium
Azide Treatments in Producing a Spatial Learning Deficit and Inhibiting Cytochrome Oxidase Activity.
Proc Natl Acad Sci U S A, (1996) 93(3): p. 1330-4, https://www.ncbi.nlm.nih.gov/pubmed/8577764.
Diamond, DM; Fleshner, M; Ingersoll, N; Rose, GM. Psychological Stress Impairs Spatial Working
Memory: Relevance to Electrophysiological Studies of Hippocampal Function. Behav Neurosci,
(1996) 110(4): p. 661-72, https://www.ncbi.nlm.nih.gov/pubmed/8864259.
Fleshner, M; Deak, T; Spencer, RL; Laudenslager, ML; Watkins, LR; Maier, SF. A Long-Term Increase in
2-Jul-19 23
Basal Levels of Corticosterone and a Decrease in Corticosteroid-Binding Globulin after Acute Stressor
Exposure. Endocrinology, (1995) 136(12): p. 5336-42.10.1210/endo.136.12.7588279.
Fleshner, M; Bellgrau, D; Watkins, LR; Laudenslager, ML; Maier, SF. Stress-Induced Reduction in the Rat
Mixed Lymphocyte Reaction Is Due to Macrophages and Not to Changes in T Cell Phenotypes. J
Neuroimmunol, (1995) 56(1): p. 45-52, https://www.ncbi.nlm.nih.gov/pubmed/7822481.
Fleshner, M; Hermann, J; Lockwood, LL; Laudenslager, ML; Watkins, LR; Maier, SF. Stressed Rats Fail to
Expand the Cd45rc+Cd4+ (Th1-Like) T Cell Subset in Response to Klh: Possible Involvement of Ifn-
Gamma. Brain Behav Immun, (1995) 9(2): p. 101-12.10.1006/brbi.1995.1011.
Fleshner, M; Goehler, LE; Hermann, J; Relton, JK; Maier, SF; Watkins, LR. Interleukin-1 Beta Induced
Corticosterone Elevation and Hypothalamic Ne Depletion Is Vagally Mediated. Brain Res Bull, (1995)
37(6): p. 605-10, https://www.ncbi.nlm.nih.gov/pubmed/7670884.
Diamond, DM; Branch, BJ; Fleshner, M. Rose, GM; Effects of Dehydroepiandrosterone Sulfate (DHEAS)
and stress on hippocampal electrophysiological plasticity, Annals of NYAS: DHEA and Aging, 774
(1995) 304-307.
Diamond, DM; Fleshner, M; Rose, GM. Psychological Stress Repeatedly Blocks Hippocampal Primed
Burst Potentiation in Behaving Rats. Behav Brain Res, (1994) 62(1): p. 1-9,
https://www.ncbi.nlm.nih.gov/pubmed/7917027.
Laudenslager, ML; Fleshner, M. Stress and Immunity: Of mice, monkeys, models and mechanisms. The
Handbook of Human Stress and Immunity, Academic Press, Glaser, R; Kiecolt-Glaser, J; Eds. (1994)
161-181.
Maier, SF; Watkins, LR; Fleshner, M. Psychoneuroimmunology. The Interface between Behavior, Brain,
and Immunity. Am Psychol, (1994) 49(12): p. 1004-17,
https://www.ncbi.nlm.nih.gov/pubmed/7818221.
Sutton, LC; Fleshner, M; Mazzeo, R; Maier, SF; Watkins, LR. A Permissive Role of Corticosterone in an
Opioid Form of Stress-Induced Analgesia: Blockade of Opiate Analgesia Is Not Due to Stress-Induced
Hormone Release. Brain Res, (1994) 663(1): p. 19-29,
https://www.ncbi.nlm.nih.gov/pubmed/7850467.
Lockwood, L.L., L.H. Silbert, Fleshner, M., M.L. Laudenslager, L.R. Watkins, and S.F. Maier, Morphineinduced
decreases in in vivo antibody responses. Brain Behav Immun, (1994) 8(1): p. 24-36.
Thomas-Dobersen, DA; Butler-Simon, N; Fleshner, M. Evaluation of a Weight Management Intervention
Program in Adolescents with Insulin-Dependent Diabetes Mellitus. J Am Diet Assoc, (1993) 93(5): p.
535-40, https://www.ncbi.nlm.nih.gov/pubmed/8315162.
Grisel, JE; Fleshner, M; Watkins, LR; Maier, SF. Opioid and Nonopioid Interactions in Two Forms of
Stress-Induced Analgesia. Pharmacol Biochem Behav, (1993) 45(1): p. 161-72,
https://www.ncbi.nlm.nih.gov/pubmed/8516354.
Fleshner, M; Brohm, MM; Laudenslager, ML; Watkins, LR; Maier, SF. Modulation of the in Vivo Antibody
2-Jul-19 24
Response by a Benzodiazepine Inverse Agonist (Dmcm) Administered Centrally or Peripherally.
Physiol Behav, (1993) 54(6): p. 1149-54, https://www.ncbi.nlm.nih.gov/pubmed/8295955.
Fleshner, M; Watkins, LR; Lockwood, LL; Grahn, RE; Gerhardt, G; Meaney, MJ; Laudenslager, ML; Maier,
SF. Blockade of the Hypothalamic-Pituitary-Adrenal Response to Stress by Intraventricular Injection
of Dexamethasone: A Method for Studying the Stress-Induced Peripheral Effects of Glucocorticoids.
Psychoneuroendocrinology, (1993) 18(4): p. 251-63,
https://www.ncbi.nlm.nih.gov/pubmed/8391148.
Diamond, DM; Bennett, MC; Fleshner, M; Rose, GM. Inverted-U Relationship between the Level of
Peripheral Corticosterone and the Magnitude of Hippocampal Primed Burst Potentiation.
Hippocampus, (1992) 2(4): p. 421-30.10.1002/hipo.450020409.
Fleshner, M; Watkins, LR; Lockwood, LL; Bellgrau, D; Laudenslager, ML; Maier, SF. Specific Changes in
Lymphocyte Subpopulations: A Potential Mechanism for Stress-Induced Immunomodulation. J
Neuroimmunol, (1992) 41(2): p. 131-42, https://www.ncbi.nlm.nih.gov/pubmed/1469075.
Fleshner, M; Watkins, LR; Redd, JM; Kruse, CA; Bellgrau, D. A 9l Gliosarcoma Transplantation Model for
Studying Adoptive Immunotherapy into the Brains of Conscious Rats. Cell Transplant, (1992) 1(4): p.
307-12, https://www.ncbi.nlm.nih.gov/pubmed/1344303.
Diamond, DM; Bennett, MC; Fleshner, M. Rose, GM; Modulation of hippocampal primed burst
potentiation by stress and corticosterone. Peripheral Signaling of the Brain: Role in Neural-Immune
Interactions and Cognitive Function, Fredrickson, RCA; Felton, DL; McGaugh, JI; Eds.; Hogrefe and
Huber, Toronto (1991) 503-508.
Barnes, CA; Forster, MJ; Fleshner, M; Ahanotu, EN; Laudenslager, ML; Mazzeo, RS; Maier, SF; Lal, H.
Exercise Does Not Modify Spatial Memory, Brain Autoimmunity, or Antibody Response in Aged F-
344 Rats. Neurobiol Aging, (1991) 12(1): p. 47-53,
https://www.ncbi.nlm.nih.gov/pubmed/2002883.
Bennett, CM; Diamond, DM; Fleshner, M. Rose, GM; Serum corticosterone level predicts the magnitude
of hippocampal primed burst potentiation in urethane-anesthetized rats. Psychobiology, 19(4)
(1991) 301-307.
Engstrom, DA; Bennett, MC; Stevens, KE; Wilson, RL; Diamond, DM; Fleshner, M; Rose, GM. Modulation
of Hippocampal Primed Burst Potentiation by Anesthesia. Brain Res, (1990) 521(1-2): p. 148-52,
https://www.ncbi.nlm.nih.gov/pubmed/2207654.
Watkins, LR; Thurston, CL; Fleshner, M. Phenylephrine-Induced Antinociception: Investigations of
Potential Neural and Endocrine Bases. Brain Res, (1990) 528(2): p. 273-84,
https://www.ncbi.nlm.nih.gov/pubmed/2271928.
Fleshner, M; Laudenslager, ML; Simons, L; Maier, SF. Reduced Serum Antibodies Associated with Social
Defeat in Rats. Physiol Behav, (1989) 45(6): p. 1183-7,
https://www.ncbi.nlm.nih.gov/pubmed/2813542.
Diamond, DM; Bennett, MC; Engstrom, DA; Fleshner, M; Rose, GM. Adrenalectomy Reduces the
2-Jul-19 25
Threshold for Hippocampal Primed Burst Potentiation in the Anesthetized Rat. Brain Res, (1989)
492(1-2): p. 356-60, https://www.ncbi.nlm.nih.gov/pubmed/2752305.
Laudenslager, ML; Fleshner, M; Hofstadter, P; Held, PE; Simons, L; Maier, SF. Suppression of Specific
Antibody Production by Inescapable Shock: Stability under Varying Conditions. Brain Behav Immun,
(1988) 2(2): p. 92-101, https://www.ncbi.nlm.nih.gov/pubmed/3148338.
VIII. PROFESSIONAL SEMINARS
i. International________________________________________________
* indicates the first author is/was a student or postdoctoral fellow supervised by Dr. Fleshner
Fleshner, M. Impacts of exercise and prebiotic dietary substrates on mind and body: The role of the gut
microbiome/metabolome. Invited Speaker, 14th International Society of Exercise Immunology
Symposium, Shanghai, China (2019).
Fleshner, M. Microbial modulatory dietary substrates promote stress robustness, Invited Speaker, 9th
Mind-Body Interface International Symposium, Taichung, Taiwan (2019).
Fleshner, M. Integrative stress physiology: Brain, Behavior & Immunity, Invited Speaker, Norman
Cousins Award, https://www.pnirs.org/society/society_awards.cfm, Psychoneuroimmunology
Research Society, Berlin, Germany (2019).
Fleshner, M. Dietary prebiotic supplements prevent stress-evoked sleep disruptions, anxiety and gut
microbial dysbiosis, Invited Speaker, 6th Beneficial Microbes Conference, Amsterdam, The
Netherlands (2017).
Fleshner, M. Early Life Exercise Promotes Changes in Gut Microbial Ecology, Persistent Stress
Robustness & Metabolic Health, Invited Speaker, The International Society of Exercise Immunology,
Coimbra, Portugal (2017).
Fleshner, M. Acute Stressor Exposure Modulates Plasma Exosomal miRNA cargo and Hsp72 expression.
Invited Speaker, The First International Congress: DAMPs, Guanajuato, Mexico (2016).
Fleshner, M. The Neurobiology and Physiology of Exercise-Induced Stress Robustness. The 2016 Arthur
C. Guyton Distinguished Lectureship Award. The Association of Chairs and Directors of
Departments of Physiology, Cabo San Lucas, Mexico (2016).
Fleshner, M. Gut Microbiome Promotes Stress Robustness, Invited Speaker, International Society for
Exercise Immunology, Vienna, Austria (2015).
Fleshner, M. Exercise and stress robustness: Benefits for physical and mental health. Invited Speaker,
University of Adelaide, Adelaide, Australia (2013).
Fleshner, M. A healthy mind in a healthy body: Impacts of exercise on stress robustness. Presidential
Symposium, International Society for Exercise Immunology, Newcastle, Australia (2013).
Fleshner, M. Stress and Immunity. Invited speaker, Corsi Residenziali Di Neuroimmunolgia. Centro
Congressi Giovanni XXIII, Bergamo-Italy (2013).
Fleshner, M. Stress-evoked sterile inflammation is modulated by physical fitness. Keynote speaker, 1st
2-Jul-19 26
Brazilian Symposium of Immunology and Sport, Sao Paulo, Brazil (2013).
Fleshner, M. Exercise produces stress resistance: Benefits for mental and physical health. Keynote
speaker, International Society for Exercise Immunology, Oxford, England (2011).
Fleshner, M; Maslanik, T; Tannura, K; Mahaffey, L; Bennison, L. The role of the gut microbiota in the
acute stressor evoked sterile inflammatory response. Invited speaker, International Society for
Exercise Immunology, Oxford, England (2011).
Fleshner, M. Exosome-associated extracellular heat shock protein 72 is released by stress and functions
as a DAMP. Psychoneuroimmunology Research Society, Dublin, Ireland (2010).
Fleshner, M. Exercise and central autonomic regulation: Mechanisms for the protective effect of
exercise on stress-induced immunosuppresssion. International Society of Exercise Immunology,
Tubingen, Germany (2009).
Fleshner, M. Extracellular Hsp 72: A double edged sword for health. Psychoneuroimmonolgy Research
Society, Arcachon, France (2007).
Fleshner, M. Extracellular Hsp 72: A double-edged sword for health. International Cell Stress and
Chaperone Society, Budapest, Hungary (2007).
Fleshner, M. Elevated level of circulating cytokines and endotoxin are not necessary for the activation of
the sickness or corticosterone responses produced by peripheral E. coli challenge. Physiology and
Pharmacology of Temperature Regulation, Rhodes, Greece (2004).
Fleshner, M.Extracellular Hsp72 released by stress facilitates innate immunity: In vivo and in vitro
support. Psychoneuroimmunology Research Society, Titisee, Germany (2004).
Fleshner, M.Hsps and the general stress response. First International Congress on Stress Responses in
Biology and Medicine. Quebec City, Canada (2003).
Fleshner, M. Stress, heat shock proteins and innate immunity: “The danger signal hypothesis”.
International Society for Exercise Immunology, Copenhagen, Denmark (2003).
Elphick, GF*; Fleshner, M. B-1 cell depletion attenuates the enhanced E.coli clearance in physically
active rats. International Society for Exercise Immunology, Copenhagen, Denmark (2003).
Fleshner, M. Leem, T; Campisi, J; Greenwood BN; The potential role of heat shock proteins in stressinduced
modulation of innate and acquired immunity. Psychoneuroimmunology Research Society,
Utrecht, Netherlands (2001).
Fleshner, M. Neuroendocrine regulation of the antibody response. The International Society of Exercise
and Immunology IV, Rome, Italy (1999).
Fleshner, M. Leem, T; Kintzel, J; Moraska, A; Deak, T; Smith, TP; Physical activity facilitates bacterial
inflammation resolution produced by stress. The International Society of Exercise and Immunology
IV, Rome, Italy (1999).
ii. Domestic___________________________________________________
* indicates the first author is/was a student or postdoctoral fellow supervised by Dr. Fleshner
2-Jul-19 27
Fleshner, M. Prebiotics, Probiotics, and a Stress Robust Phenotype. Center for Neuroscience, University
of Colorado-Boulder, Colloquium (2019) Invited Speaker.
Fleshner, M. Dietary Prebiotics Impact Gut Microbiome and Metabolome: A Successful Countermeasure
for Improving Resilience to Sleep & Circadian Disruption, Integrative Physiology, University of
Colorado-Boulder, Departmental Colloquium (2018) Invited Speaker.
Fleshner, M. Dietary prebiotics & stress resistance: Impacts on the brain, sleep, inflammation and the
gut microbiome/metabolome, Probiota Americas, Miami, Florida (2018) Invited Speaker.
Fleshner, M. Inflammatory Homeostasis: A role for MAMPs, DAMPs and microRNA, Experimental
Biology, San Diego, CA (2018) Invited Speaker.
Thompson RS*; Bowers SJ; Gonzalez A; Vargas F; Wright KP Jr; Lowry CA; Vitaterna MH; Turek FW, Knight
R; Dorrestein PC; Fleshner M. Gut Microbial Modulatory Diet Reduces the Impact of Chronic
Circadian Disruption on Sleep and Facilitates Rhythm Realignment, Society for Research on
Biological Rhythms, Amelia Island, Florida (2018) Selected Speaker.
Fleshner, M. Stress evoked sterile inflammation: A role for MAMPs, DAMPs and microRNA, Colorado
State University, Health and Exercise Science Spring Seminar Series, Fort Collins, CO (2018) Invited
Speaker.
Fleshner, M. Early life exercise promotes favorable changes in gut microbial ecology, persistent stress
robustness, and metabolic health, Duke University School of Medicine Interdisciplinary Symposium,
Raleigh-Durham, North Carolina (2017) Invited Speaker.
Fleshner, M. Inflammatory Homeostasis: A role for MAMPs, DAMPs and microRNA, Integrative
Physiology, University of Colorado-Boulder, Departmental Colloquium (2017) Invited Speaker.
Fleshner, M. Early life exercise promotes favorable changes in gut microbial ecology, persistent stress
robustness and metabolic health, Department of Integrative Biology, University of Colorado-Denver,
Fall Seminar Series (2017), Invited Speaker.
Fleshner, M. The neurobiology and physiology of exercise-induced stress robustness. ACSM: World
Congress on the Basic Science of Exercise and the Brain, Denver CO (2017), Invited Speaker.
Fleshner, M. Prebiotic diet modulates the impact of stress on REM sleep. The Colorado Sleep and
Circadian Research Symposium, The University of Colorado, Boulder, CO (2016), Invited Speaker.
Fleshner, M. Danger signals, microRNA and the inflammasome: Stress-evoked sterile inflammation and
its relevance in mood disorders. American College of Neuropsychopharmacology, Hollywood, FL
(2016), Invited Speaker.
Fleshner, M. Exercise induces stress robustness across the lifespan: The role of the gut microbiota. The
Integrative Biology of Exercise, American Physiological Society, Phoenix, AZ (2016), Invited Speaker.
Fleshner, M. Exercise induces stress robustness across the lifespan: The role of the gut microbiota.
Cousins Center Lectures in Psychoneuroimmunology (PNI) at UCLA School of Medicine. Los Angeles,
2-Jul-19 28
CA (2016), Invited Speaker.
Fleshner, M. Early life prebiotic diet promotes sleep and stress robustness. Gordon Conference on Sleep,
Galveston, TX (2016), Invited Speaker.
Fleshner, M. Early life exercise and the gut microbiota: Long lasting impacts on brain, stress resistance,
and metabolism. Neurobiology of Learning and Memory, 40th Anniversary. Park City, UT (2016).
Fleshner, M. Promoting Stress Robustness. Georgia State University, Neuroscience Institute
Distinguished Lecture Series, Atlanta, GE (2015), Invited Speaker.
Fleshner, M. Stress, Exercise and Sleep. University of Colorado School of Medicine Anschutz,
Department of Neurology, Resident Sleep Seminar, Denver, CO (2015).
Fleshner, M. Exercise promotes stress robustness: Modulation of brain serotonin neurocircuitry.
University of Colorado Anschutz Medical Campus, Integrated Physiology Graduate Program
Seminar, Denver, CO (2015).
Fleshner, M. Protecting our troops from damaging stress. University of Northern Colorado School of
Biological Sciences Symposium, Greeley, CO (2015).
Fleshner, M. Acute stressor exposure modulates plasma exosomal miRNA and Hsp72 cargo. Academic
Health Research Seminars University of Minnesota School of Medicine, Duluth, MN (2014).
Fleshner, M. Rhythm disruptions and stress sensitization. The Colorado Sleep and Circadian Research
Symposium, The University of Colorado, Boulder, CO (2014).
Fleshner, M. Exercise promotes stress robustness. The Society for Neuroscience (Exercise, energy intake,
and the brain, selected symposium). Washington, DC (2014).
Fleshner, M. Exercise and prebiotic modulation of the gut microbiome promotes stress robustness. The
Psychoneuroimmunology Research Society, (Integrating the microbiome into PNI paradigm and
Mind/Body science, selected symposium). Philadelphia, PA (2014).
Fleshner, M. Acute stressor exposure modulates plasma exosomal miRNA and Hsp72 cargo. The Seventh
International Symposium on Heat Shock Proteins in Biology and Medicine. Washington, DC (2014).
Fleshner, M. Disruptions in body temperature rhythms predict stress sensitization. The International
Behavioral Neuroscience Society, Las Vegas, NV (2014).
Fleshner, M. Mindful movement and movement of the minds. The Diversity Summit, University of
Colorado at Boulder.
Fleshner, M. Exercise promotes stress robustness. The American College of Neuropsychopharmacology,
Phoenix, AZ (2014) selected symposium.
Fleshner, M. Putting the ice on stress, aging and CNS trauma. Winter Conference on Brain Research,
Steamboat, CO (2014).
2-Jul-19 29
Fleshner, M. Extracellular Hsp72 is a DAMP released by stress. Experimental Biology, Boston, MA
(2013). https://www.webges.com/cslide/e02816c/public/play_video/19 (ACVP Symposium: Inside-
Out- Extracellular Roles for Heat Shock Proteins)
Fleshner, M. Protecting our troops from damaging stress. Center for Neuroscience seminar, University of
Colorado, Boulder, CO (2013).
Fleshner, M. Novel gene targets of exercise-induced stress resistance in the dorsal raphe nucleus.
Winter Conference on Brain Research, Breckenridge, CO (2013).
Fleshner, M. Impact of physical activity on stress robustness, Department of Physiology & Neurobiology,
Dartmouth, Lebanon NH (2013).
Fleshner, M. Exercise and stress “robustness”: Benefits for physical and mental health. Department of
Psychology and Neuroscience, Duke University, Durham, NC (2012).
Fleshner, M. Protecting our troops from damaging stress. IPHY seminar, University of Colorado, Boulder,
CO (2012).
Fleshner, M. Exercise and stress resistance and resilience: Benefits for mental and physical health.
University of Vermont Macmillan Symposium, Keynote Lecture (includes webcast to local colleges
and high schools). Burlington, VT (2012).
Fleshner, M. Stress, inflammasomes and sterile inflammation. Presidential Symposium Lecture,
Psychoneuroimmunology Research Society, San Diego, CA (2012).
Fleshner, M. DAMPs, MAMPs, & the Inflammasome in Stress-Evoked Sterlie Inflammatory Protein
Responses. Presidential Symposium Lecture, Society for Behavioral Neuroendocrinology, Madison,
WI (2012).
Fleshner, M. Exercise and stress resistance and resilience: Benefits for mental and physical health.
Biology Department Colloquium, Kent State University, Kent, OH (2011).
Fleshner, M. Exercise and stress resistance and resilience. School of Life Sciences Lecture Series, Arizona
State University, Tempe, AZ (2011).
Fleshner, M. Stress, DAMPs and Immunomodulation. Society for Leukocyte Biology
Meeting PNIRS Symposium, Kansas City, MO (2011).
Fleshner, M. Extracellular Hsp72 is an endogenous DAMP released by stress. Biological and
Immunological Sciences Seminar, Ohio State University, Columbus, OH (2011).
Fleshner, M. Stress & Immunity in Experimental Animal Models. PNIRS Educational Short Course,
Chicago, IL (2011).
Fleshner, M. Endogenous Hsp72: Releasing signals, cellular sources & releasing pathways. Graduate PNI
Seminar, University of Denver, Denver, CO (2010).
2-Jul-19 30
Fleshner, M. Enabling stress resistance with exercise. Neuroscience Seminar, University of Illinois,
Champaign, IL (2010).
Fleshner, M. Exercise and stress resistance: From brain to behavior. Winter Brain Conference,
Breckenridge, CO (2010).
Fleshner, M. Enabling stress resistance with controllable exercise: Affective consequences and 5HT
mechanisms. Neuroscience Colloquium, Smith College, Northhampton, MA (2010).
Fleshner, M. The stress buffering effects of exercise: Immune consequences & SNS mechanisms. Biology
Colloquium, Smith College, Northhampton, MA (2010).
Fleshner, M. The stress buffering effects of exercise. The Neurobiology of Stress Workshop, Session
Chair, Boulder, CO (2010).
Fleshner, M. The stress buffering effects of exercise. The Winter Brain Conference on the Neurobiology
of Learning and Memory, Park City, Utah (2009).
Fleshner, M. Endogenous alarm signals: Immune consequences, releasing signals, and cellular sources.
Integrated Biomedical Science Seminar Series, Loma Linda, CA (2008).
Fleshner, M. Extracellular Hsp72: Releasing signals and cellular source. Integrative Physiology seminar,
University of Colorado, Boulder, CO (2008).
Fleshner, M. Extracelluar Hsp72: A double-edged sword for health. Center for Neuroscience seminar,
University of Colorado, Boulder, CO (2008).
Fleshner, M. Exercise and stress resistance: Neural mechanisms and health consequences. The Repole
Lecture, University of Vermont, Birminghan VT (2007).
Fleshner, M. Exercise and stress resistance: Neural mechanisms and health consequences. University of
California-Irvine, Irvine, CA (2007).
Fleshner, M. Exercise and stress resistance: Neural mechanisms and health consequences. Integrative
Physiology seminar, University of Colorado, Boulder, CO (2007).
Fleshner, M. Exercise and stress resistance: Neural mechanisms and immunological consequences.
Anatomy and Physiology seminar, Kansas State University, Manhattan, KA (2006).
Fleshner, M. Extracellular Hsp 72: A double-edged sword for health. Integrative Physiology seminar,
University of Colorado, Boulder, CO (2006).
Fleshner, M. The protective effect of physical activity on stress-induced immunosuppression:
neuroendocrine mechanisms. Department of Physiology and Neuroscience, University of Colorado
Health and Science Center, Denver, CO (2006).
Fleshner, M. Extracellular Hsp 72: A double edged sword for host defense. Pediatrics seminar, University
of California-Irvine, Irvine, CA (2006).
Fleshner, M. Physical activity suppresses the negative effect of stress: A systems biology approach.
Health and Exercise Science seminar, Colorado State University, Fort Collins, CO. (2006).
Fleshner, M. Physical activity and tyrosine supplementation-Two effective interventions that prevent
2-Jul-19 31
stress-induced immunosuppression: Implications for aging. Keynote Speaker, Seminar workshop of
Center for Aging and the Life Course, Purdue University, West Lafayette, IN (2005).
Fleshner, M. Sympathetic nervous system activation stimulates the release of heat shock protein 72 into
the circulation: Potential immunological consequences. NIH Biodefense workshop, Integrative
Neural Immune Program. Washington, DC (2005).
Fleshner, M. Adaptations in 5HT systems produced by exercise prevents stress-induced affective
dysregulation. Winter Conference on Brain Research, Winter Park, CO (2005).
Fleshner, M. Endogenous Hsp72 is released by catecholamines and may function as a “danger signal” for
immunity. American Association of Immunologists (2005).
Fleshner, M. Physical activity reduces the negative effects of stress on behavior, neural, endocrine and
immune responses. Keynote Address, American College of Sports Medicine (2005).
Fleshner, M. Exercise and Stress Resistance: A Systems Biology Approach. Pennington Research
Conference Series, Baton Rouge, Louisiana. (2004).
Fleshner, M. The protective effect of physical activity on stress-induced immunosuppression:
Neuroendocrine mechanisms. Integrative Neuroscience Colloquium Series, Marquette University,
Milwaukee, WI (2004).
Fleshner, M. Exercise prevent s learned helplessness: The role of serotonin. Susan Samueli Center for
Complementary and Alternative Medicine, College of Medicine, University of California-Irvine,
Irvine, CA (2004).
Fleshner, M. Heat shock proteins and the stress response: Implications for immunity. School of Medicine
Basic Science Seminar Series, Loma Linda University, Loma Linda, CA (2004).
Fleshner, M. Heat shock proteins and the stress response: Danger signals for immunity. Immunology
Seminar Program, Department of Medicine, Ohio State University, Columbus, OH (2004).
Fleshner, M. The neurobiology of the stress resistant brain. Integrative Physiology Colloquium series.
University of Colorado, Boulder CO (2004).
Fleshner, M. A sedentary lifestyle reduces stress resistance. Department of Kinesiology, University of
Illinois, Urbana, IL (2003).
Fleshner, M. Possible mechanisms of activation on the innate immune system by non-immune stressors:
“The danger signal” hypothesis. Presidential symposium, Psychoneuroimmunology Research
Society, Ameila Island, Florida (2003).
Fleshner, M. Stress, inflammation and heat shock proteins. American College of Sports Medicine,
Featured session, San Francisco, CA (2003).
Fleshner, M. Stress-induced extracellular HSP72 is a functionally significant "danger signal to the
immune system”. American Association of Immunologists and International Society for
NeuroImmunoModulation (ISNIM), Guest symposium. Denver, CO (2003).
Fleshner, M. Exercise prevents learned helplessness: The role of 5HT. Neuroscience Seminar Series,
University of Colorado, Boulder CO (2003).
2-Jul-19 32
Fleshner, M. A sedentary lifestyle reduces stress-resistance. Institute of Behavioral Science, Population
and Health Seminar, University of Colorado, Boulder CO (2003).
Fleshner, M. Physical Activity and Depression: Neural mechanisms. Introduction to Neuroscience II,
University of Colorado, Boulder CO (2003).
Fleshner, M. The immune system and its relationship to pain. Internal Medicine Review: Pueblo
Association for Interest in Neuroscience and TMD Study, Peublo, CO (2002).
Fleshner, M. The physiology of the stress response in sedentary and physically active organisms”. Rocky
Mountain chapter of the American College of Sports Medicine, Fort Collins, CO (2002)
Fleshner, M. The stress-susceptibility of a sedentary lifestyle. University of Colorado Health Sciences
Center, Center for Nutrition seminar, Denver, CO (2002).
Fleshner, M. The stress susceptibility of a sedentary lifestyle: Brain neurocircuitry. Department of
Neuroscience Seminar Series, University of Virginia (2001).
Fleshner, M. The immune system: A tutorial. The Summer Institute for Psychoneuroimmunology
Research II, University of Washington (2000).
Fleshner, M. Stress-induced extracellular HPS72 is a functionally significant “danger signal” to the
immune system. Basic Science Conference, The Division of Medical Oncology, University of Colorado
Health Sciences Center, Denver, CO (2002).
Fleshner, M. Heat shock proteins and inflammation: The body’s “danger signal”, American Association of
Immunologists and PNIRS Guest symposium, New Orleans, Louisiana (2002).
Fleshner, M. Campisi, J; Miller, JK; Kennedy, SL; Smith, TP; Physical activity reduced circulating and
tissue cytokine and sympathetic responses to stress. Psychoneuroimmunology Research Society,
Madison, Wisconsin (2002).
Fleshner, M. Leem, T; Campisi, J; Greenwood BN; The potential role of heat shock proteins in stressinduced
modulation of innate and acquired immunity. The International Society of Exercise
Immunology, Baltimore, MD (2001).
Maier, SF; Nguyen, KT; Watkins, LR; Fleshner, M. Acute stress suppresses the KLH-specific but not
mitogenic (ConA) proliferative response. Research Perspectives in Psychoneuroimmunology, VIII,
(1998).
Fleshner, M. Moraska, A; The protective effect of exercise on stress-induced suppression of the specific
antibody response. Research Perspectives in Psychoneuroimmunology, VIII, (1998).
Fleshner, M. The interface between brain, behavior and immunity: Is stress always bad? The 19th
annual conference of the New York Neuropsychology Group and New York Academy of Science, New
York, NY (1998).
Fleshner, M. Stress, Exercise and Immunity. The Summer Institute for Psychoneuroimmunology
Research, University of Washington, Seattle, WA (1998).
Moraska, A*; Nguyen, KT; Mazzeo, RM; Roth, DA; Fleshner, M. Voluntary exercise potentiates whereas
forced exercise suppresses anti-KLH responses. Research Perspectives in Psychoneuroimmunology,
2-Jul-19 33
VII. (1997).
Fleshner, M. Nguyen, KT; Effects of unweighting on innate and specific immunity. Aerospace
Gravitational and Space Biology XII, Charlotte, NC (1996).
Fleshner, M. Watkins, LR; Laudenslager, ML; Maier, SF; A CD4+ T cell shift from Th1 to Th2: A
mechanism of stress-induced reduction of the KLH-specific antibody response. Research
Perspectives in Psychoneuroimmunology, V, (1994).
Fleshner, M. Stress-induced reduction in MLR is dependent on macrophages but not on changes in
phenotypes. Research Perspectives in Psychoneuroimmunology, IV, (1993).
Fleshner, M. Watkins, LR; Lockwood, LL; Bellgrau, D; Laudenslager, ML; Maier, SF; Stress-Induced
Changes in CD4+ and CD8+ Lymphocytes. NIMH Research Training Directors Meeting, Bethesda, MD
(1991).
iii. Administrative
Fleshner M. Ways to get your scholarly work off to a great start. Faculty Fair, Office of the Vice
Chancellor for Research, Boulder, CO (2013).
Fleshner M. Seed grants, competitions, applications and awards. Faculty Fair, Office of the Vice
Chancellor for Research, Boulder, CO (2012).
Fleshner M. Level 1 Research. Postdoc Career Development Retreat, Denver, CO (2013).
IX. SERVICE
i. Departmental________________________________________________
1998, 2001 Faculty Search Committee, member
2002, 2008, 2010 Faculty Search Committee, member
2005-2006 Faculty Search Committee, Chair
2003-2008 Graduate Admissions Committee
2003-2013 Future Hiring/Steering Committee
2005-2013 Strategic Planning Committee
2005 Grievance Committee (special appointment)
2005 Tenure and Promotion Committee (Pei-San Sei)
2006-2008 Identity Task Force Committee, Chair
2008 Tenure and Promotion Committee PEUC (Wright)
2009-2010 Tenure and Promotion Committee PEUC (Allen)
2010-2011 IPHY Student Board Lecture
2011 Tenure and Promotion Committee PEUC (Tsai, Chair)
2011 Program Review: Space and Infrastructure, Chair
2011 Awards Committee, Chair
2010-2013 Welfare Committee, Chair
2005-2013 Space Committee, Chair
2014 Tenure and Promotion Committee PUEC (Wright, Chair)
2015-2016 Search Committee, Joint IPHY/PSYCH, Chair
2015-present Wilderness Place Space Committee
2017-present IPHY Executive Committee
2-Jul-19 34
ii. University_______________________________________________
1997 Dean’s Master Plan Task Force
1997-2007 Institutional Animal Care & Use Committee (IACUC) Co-Chair
1998 Undergraduate Honor’s Council
1999-2002 Neuroscience Ph.D. Steering/Curriculum Committee
2002-present Neuroscience Ph.D. Admissions Committee
2004-2009 Integrative Physiology Graduate Admissions Committee
2005 McNair Program Summer Minority Research Opportunity Program
2006-2011 Biological Science Initiative Faculty Board
2007-2011 Executive Advisory Committee
2009-2011 East Campus Advisory Committee
2010 VC for Research Office IT Search Committee, Chair
2011 LEAP/Faculty Affairs Workshop “Management”
2011-2012 College of Arts and Sciences Dean’s Search Committee (40+ hrs)
2012 CV Workshop (Postdoctoral Association)
2012-2013 Vice Chancellor for Research: Research Review Board (2 hrs per month)
2012-2013 Office of Animal Research OLAW Assurance Task Force (3 hrs per wk)
2009-2013 Faculty Associate to the Vice Chancellor for Research
2010-2014 College of Arts and Sciences Personnel and Tenure Committee (20 hrs per mo)
2012-2014 Boulder Faculty Assembly Budget and Finance Committee (1 hr per wk)
2013-2016 Academic Affairs Budget Advisory Committee
2014-2016 Boulder Faculty Assembly Budget and Finance Committee (Chair, 1 hr per wk)
2014-2016 Boulder Faculty Assembly Executive Committee (1 hr per wk)
2014 Boulder Faculty Assembly Discrimination/Harassment Policy and Procedure
2015 Carlson Renovation and Re-purposing Committee
2016 Academic Review and Planning Advisory Committee (ARPC)
2016 Leeds External Personnel Actions Committee
2016 Base Budget Steering Committee
2016 BFA Research Awards Committee (chair)
2015-2017 Associate Vice Chancellor Advisory Committee (AVC)
2015-present Radiation Safety Committee (2 hr per mo)
2016-present College of Arts & Sciences Dean’s Budget Committee (2 hr per mo)
iii. Professional________________________________________________
Journal Reviewer (selected list):
American Journal of Reproductive Immunology
American Journal of Physiology
Behavioral Brain Research
Biological Psychiatry
Brain, Behavior and Immunity
Brain Research
Behavioral Neuroscience
Cell Biochemistry and Function
Developmental Psychobiology
European Journal of Physiology
Exercise Science and Sport Reviews
Expert Reviews in Vaccines
Frontiers
2-Jul-19 35
International Journal of Behavioral Medicine
Journal of Applied Physiology
Journal of Immunology
Journal of Neuroscience
Journal of Neuroimmunology
Journal of Gerontology: Medical Sciences
Neuroscience
Neurosignals
Neurobiology of Aging
Physiology and Behavior
Pharmacology, Biochemistry, and Behavior
PlosONE
Psychopharmacology
Psychosomatic Medicine
Stress: The International Journal on the Biology of Stress
Synapse
Journal Editor:
2002-2005 Assistant Editor: Exercise Science and Sport Reviews
2002-2007 Editorial Board: Journal of Applied Physiology
2011-2013 Section Editor: BioMedCentral: Physiology
2008-2014 Editorial Board: Frontiers in Neuroscience
2011-2016 Editorial Board: Brain, Behavior and Immunity
2017-2018 Special Issue Editor: Brain, Behavior and Immunity
2014-2019 Editorial Board: The Neurobiology of Stress
Grant Reviewer:
1999-2015 National Science Foundation (NSF)
1999-2015 Undergraduate Research Opportunities Program (UROP)
2000-2001 National Aeronautics and Space Administration (NASA)
2000 National Institutes of Health (NIH) ad hoc reviewer
2001 National Institutes of Health CSR (IFCN-2) ad hoc reviewer
2000-2001 National Aeronautics and Space Administration (NASA)
2003 National Institutes of Health: Special Emphasis Panel
2003 National Science Foundation Postdoctoral Fellowship review panel:
Microbiology, Physiology, and Neuroscience section.
2004-2008 National Institutes of Health: Neurobiology of Motivated Behavior, regular
member
2008 National Institutes of Health: Special Emphasis Panel
2008 Swiss National Science Foundation
2008 National Aeronautics and Space Administration
2010 Deutsche Forschungsgemeinshchaft (DFG) in Regensburg, Germany
2010-2012 National Institutes of Health: College of CSR Reviewers
2010 Army Research Office
2010 Medical Research Council, United Kingdom
2011 National Science Foundation Postdoctoral Fellowship Review Panel:
Microbiology and Cell Biology Section
2011 National Institutes of Health Study Section, NNRS, Baltimore, MD
2-Jul-19 36
2011 National Institutes of Health Study Section, APDA, San Francisco, CA (2011)
2012 National Institutes of Health Study Section, BBBP, Washington DC
2013 National Aeronautics and Space Administration (Immunology), Review,
Washington DC (2013).
2013 National Science Foundation, Neural Systems Cluster Integrative Organismal
Systems / BIO
2013 Inserm Institut National, Institut des sciences biologiques
2013 Netherlands Organization for Scientific Research
2015 National Institutes of Health: Neurobiology of Motivated Behavior, ad hoc.
2016 Knut and Alice Wallenberg Foundation, Stockholm, Sweden.
2016 National Institutes of Health Study Section Biobehavioral Regulation, Learning,
and Ethology (BRLE), ad hoc, Washington DC
2017 Knut and Alice Wallenberg Foundation, Stockholm, Sweden.
2017 Crohn’s and Colitis Foundation, New York, NY.
2017 NIH-National Center for Complementary and Integrative Health (NCCIH / NIH)
2018 NIH-Fellowship, Career Development, and Research Grant Programs Ad hoc
reviewer.
2018 NIH-Biobehavioral Regulation, Learning and Ethology Panel (BRLE/NIH) Ad hoc
reviewer.
2018-present Crohn’s and Colitis Foundation, Grant reviewer
2019 NIH-Helping to End Addiction Long-term (HEAL), Special Emphasis Panel,
Selected reviewer.
2019 Japan Agency for Medical Research and Development (AMED)
Selected reviewer.
Professional Society:
1990-present Society for Neuroscience, Member
2000-present International Society for Exercise Immunology, Member
1995-present Psychoneuroimmunology Research Society, Member
2001-2010 American Association of Immunologist, Member
2003-2010 Cell Stress Society International, Member
1998-2001 Psychoneuroimmunology Research Society, Nomination Committee
2000 Psychoneuroimmunology Research Society, Session Chair
1999-2001 Psychoneuroimmunology Research Society, Advisory Committee
2001 International Society for Exercise Immunology-Session Chair
2001-2004 Psychoneuroimmunology Research Society, Scientific Council (elected position)
2001-present International Society for Exercise Immunology, Scientific Program committee
2003 International Society for Exercise Immunology, Session Chair
2002-2004 Psychoneuroimmunology Research Society, Scientific Program Committee
2003 Psychoneuroimmunology Research Society, Session Chair
2005 Psychoneuroimmunology Research Society, Co-Host, Annual Meeting Denver,
CO
2004-2006 Psychoneuroimmunology Research Society-Officer Secretary/Treasurer (elected
position)
2004 Psychoneuroimmunology Research Society, Scientific Program Committee
2003-2004 American Physiological Society: Human use of animals exercise design workshop
2-Jul-19 37
2005-2006 American Physiological Society: Animal Care and Experimentation Committee
(ad hoc member)
2007-2011 American Physiological Society: Animal Care and Experimentation Committee
(Regular member)
2008-2013 Psychoneuroimmunology Research Society-Scientific Program Committee
2009 Psychoneuroimmunology Research Society-Co-Host of Annual Meeting
Breckenridge, CO
2011-2012 Psychoneuroimmunology Research Society-President (elected position)
2011-2013 International Society for Exercise Immunology (ISEI), President (elected position)
2012-2013 Psychoneuroimmunology Research Society, Election & Awards Committee, Chair
2016-2018 Industrial Hemp Research Foundation: Founding member of the board
2018-present CU-Research Education, and Application in Cannabinoids and Health: Founding
member of the board.
2018-present Psychoneuroimmunology Research Society Finance Committee
Community:
1998-2000 Community Outreach High School Research Advisor
2002 Internal Medicine Review: Pueblo Association for Interest in Neuroscience and
TMD Study
2005-2015 High School Outreach Program. Annual group lab visits and presentations to
students from inner city Denver High Schools
2011 Boulder Country Day Science Fair Judge (8 hrs)
2011 Medical Advance Community Lecture (Thorton, CO, 4 hrs)
2011-2015 Promoting Athletic Performance Recovery and Stress Resistance (PAPRR)
Development Board (+4 hrs)
2013 CU at the Library Outreach, "Exercise & stress robustness: Benefits for mental
physical health" (+5 hrs)
2015 CAPS (Counseling & Psychological Services) at CU, “Exercise Promotes Stress
Robustness”
2015 CAPS (Counseling & Psychological Services) at CU, “Exercise and Prebiotic Diet
Promotes Stress Robustness”
2012-present CU Wizards, “Immunity in Health & Disease: The Army Within” (+12 hrs per
show/per year)
X. SELECTED MEDIA RELATIONS: Featured scientist
Fleshner, M. MSNBC, November 29, 2006, “Can stress actually be good for you?”
Fleshner, M. Psychology Today, August 10, 2006, “A case for double edged optimism.”
Fleshner M; “O” The Oprah magazine, January 2007, “Why it’s so hard to change yourself”.
Fleshner, M. Body and Soul, November 2008, “Stay healthy this season.”
Fleshner, M. US World & News Report, June 2008, “Relax! Stress can be good for
you.”
Fleshner, M. PBS TV Special, November 2009, “The Science of Healing”.
2-Jul-19 38
Fleshner, M. Fitness, September 2010, “Stop stress for good.”
Fleshner, M. Doctor Radio, Sirius Radio, September 5, 2014, “Nutrition, Health and Fitness with
Samantha Heller”.
Fleshner, M. Early life exercise and the gut microbiota. January 1st 2016, Channel 7 News, 5pm, 6pm,
and 10pm. https://shar.es/16gvDZ.
Fleshner, M. Could your workout impact your gut health? Yes and here’s why. Vogue, March 25, 2016.
http://www.vogue.com/13420406/gut-health-microbiome-good-bacteria-exercise-new-studiesresearch/
Fleshner, M. Prebiotics in early life may boost sleep and daytime rhythms, 2016.
http://www.nutraingredients-usa.com/Research/Prebiotics-in-early-life-may-boost-sleep-anddaytime-
rhythms Study?utm_source=copyright&utm_medium=OnSite&utm_campaign=copyright
Calmer Waters, The Caregiver’s Journey through Alzheimer’s and Dementia, by Barbara Cohn. Blue River
Press, Indianapolis, IN. (2016). Contributing Author, “Exercise and Stress Robustness: Benefits for
Mental and Physical Health” pp 173-177.
Fleshner, M. live healthy: Sleep-Stress Connection. Shape, Sept 2017, pg. 114. https://shape.com.
XI. TEACHING
i. Graduate Seminars/Courses
Courses are each a semester in duration (3 hrs lecture/ contact per week) at the University of Colorado at
Boulder, unless otherwise indicated.
2007-present IPHY 5600 Graduate Immunology 25 students/class
2006-2013 IPHY 6830 Professional Skills, 2 lectures per year 20 students/class
2002, 2003, 2006
2013, 2016 IPHY 5100 Colloquium 25 students/class
2003-2011 ARSC 5110 Neuroscience II, 1 lecture per year 25 students/class
1998-1999 IPHY 6010 Exercise Immunology 20 students/class
1996 Behavioral Neuroscience 25 students/class
1994 Stress and Immunity 15 students/class
ii. Undergraduate Seminars/Courses
Courses are one semester in duration (3 hrs lecture/ contact per week) at the University of Colorado at
Boulder, unless otherwise indicated.
2007-present IPHY 4600 Immunology 100-200 students/class
2006 IPHY Student Board Lecture 15 students/class
2005-2006 IPHY 3600 Immunology 125 students/class
2003-2004 IPHY 4770 Mind-Body Health 75 students/class
1998-2001, 2004 IPHY 4660 Critical Thinking: Exercise Immunology 30 students/class
2002 IPHY 4750 Psychological Kinesiology 75 students/class
2001 IPHY 4100 Colloquium 30 students/class
1993, 1996 Behavioral Neuroscience, Dept of Psychology 35 students/class
2-Jul-19 39
1993, 1996 Introductory Psychology, U of Colorado-Denver 200 students/class
1995 BioPsychology, Dept of Pychology 45 students/class
1994 Behavioral Neuroscience, Un of Colorado-Denver 30 students/class
1993, 1994 Drugs and Behavior, U of CO-Denver 40 students/class
1992 Intro Psychology, Front Range Community College 40 students/class
1991 Physiological Psychology, University of Denver 20 students/class
iii. Training Grant Faculty Advisor _________________________
2018-present PI: Lindheimer, Jacob
NIH Career Development Award: GRANT12478366
Research Health Scientist | William S. Middleton Veterans Memorial Hospital
Honorary Fellow | UW-Madison Department of Kinesiology
Title: “Acute exercise tolerance among Veterans with Gulf War Illness”
iv. Supervised Trainees (Primary Mentor)_________________________
Date / Student name / Research topic
Graduate Students: Past MS Students
1997-1998 Jen Kintzel, “Exercise, stress and inflammation”, MS
1997-1998 Taro Smith, “Exercise, stress, and hormones”, MS
1998-1999 Ted Leem, “Stress and inflammation”, MS
1997-1998 Bristol Sorensen, “CFS and exercise”, MS
1998-1999 Gwen Elphick, “Exercise, stress and antibody”, MS
1999-2000 Jay Campisi, “Stress and inflammation”, MS
1999-2000 Jill Miller, “Exercise, stress and cytokines”, MS
1999-2000 Kim Hansen, “Exercise and aging”, MS
1999-2001 Danielle Stinchfield, “Exercise and Parkinson’s”, MS
1999-2001 Ben Greenwood, “Exercise, stress and c-Fos”, MS
2002-2003 Julianne West, “Microbiology of inflammation”, MS
2001-2003 Karianne Higgins, “Age and intracellular HSPs”, MS
2001-2003 Molly Nickerson, “Physical activity and brain cytokines”, MS
2004-2006 Kyle Kirby, “Stress and the DRN”, MS
2003-2006 Craig Sharkey, “Stress and Inflammation” MS
2010-2011 Arman Serebrakian, BA/MS, “ADR signaling of adipose cytokines”, MS thesis
2010-2012 Brianne Loughridge, MS, “Gene array analyses of DRN”, MS advisor
2011-2012 Justin Hellwinkel, MS, “Behavioral Consequences of Stress and Exercise on Fear
Conditioning”, MS
2011-2013 Stuart Cox, “Beta3 ADR signaling of IL1beta in adipose.” BA/MS
2011-2013 Katie Spence, “Exercise and brain plasticity”, BA/MS
2012-2014 Madeline Paton, “Stress, Nutrition and Sterile Inflammation” BA/MA
2012-2014 Jon Herrara, “The role of dopamine circuitry in the reward of exercise”, MS
2015-2017 Camille Crane, MS, “Exosomal protein expression and miRNA cargo
2015-2017 Donald Borchert, MS, “Exercise and prebiotics produce synergic effect of the gut
microbiome.
2016-2017 Rebecca Hall, “The Second Brain: The Impact of Intestinal Microbiota on
Stress-Induced Behavioral Depression”, MS
2016-2018 Rachel Roller, “Oral Phytochemical and Sterile Inflammation”, MS
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2016-2018 Michelle Gaffney, “Prebiotic diet and Cognitive Performance”, MS
Graduate Students: Past MS/PhD Students
1997-1999 Michael Pecaut, “Spaceflight and immunity”, PhD advisor
Current Position: Associate Professor, Dept of Radiation Medicine/Division of Radiobiology, Loma
Linda University
1998-2001 Albert Moraska, “Exercise, stress and antibody”, PhD advisor
Current Position: Professional Research Associate, UCHSC
1999-2003 Gwen Elphick, “nIgM and exercise”, PhD advisor
Current Position: Research Fellow, Brown Medical School
2000-2003 Jay Campisi, “Stress, Hsp and Inflammation”, MS and PhD advisor
Current Position: Associate Professor and Chair, Dept of Biology, Regis University
1998-2004 Taro Smith, “Aging and physical activity: Implications for human immune
Current Position function and health”, PhD advisor, Product Development
1999-2005 Sarah Kennedy, “Exercise, stress and catecholamines”, PhD advisor
Current Position: Medical Science Liaison, Immunology, UCB Pharmaceuticals
2001-2005 Ben Greenwood, “Neurocircuitry of stress”, PhD advisor
Current Position: Assistant Professor, Psychology, University of Colorado at Denver
2001-2006 Molly Nickerson, “A role for estrogen in the expression of heat shock protein
Current Position: 72”, PhD advisor, Translational Medical Scientist at Mitsubishi Tanabe Pharma
2002-2009 Teresa Foley, “The neurobiology of exercise”, MS advisor, PhD advisor.
Current Position: Science Education Fellow & Senior Instructor, IPHY, University of Colorado
2007-2012 Paul Strong, “Neurobiology, stress and exercise”, MS advisor, PhD advisor
Current Position: Scientific Communications Manager, Medical Affairs, Spectranetics Inc.
2007-2012 Tom Maslanik, “Stress-induced sterile inflammatory responses” MS/PhD
Current Position: Product Manager, Novus Biologicals
2008-2012 Kristin Speaker, “The effects of habitual exercise and fasting on stress-evoked
cytokine expression in non-obese white adipose tissue”, PhD
Current Position: Postdoctoral Fellow & Transformational Weight Loss Coach, Anschutz Health
and Wellness Center, Denver, CO
2006-2013 Robert Thompson, “Biotelemetric analyses of stress physiology: The impact of
stressor chronicity, stressor controllability and exercise" MS/PhD
Current Position: Postdoctoral Fellow, Department of Integrative Physiology
2007-2013 Lida Beninson, "The emerging role of exosomes in stress physiology" MS/PhD
2-Jul-19 41
Current Position: National Academy of Sciences, Program Officer, Washington, DC.
2012-2016 Aggie Mika, “The long-term impact of exercise across the lifespan”, PhD advisor
Current Position: Medical Associate, Health Care Consultancy Group, NY, NY.
Postdoctoral Fellows: Past Fellows
2002-2007 John D. Johnson, PhD, Postdoctoral Fellow Mentor,
Current Position: Associate Professor, Neuroscience Dept, Kent State University
2006-2007 Josh Friedman, PhD, Postdoctoral Fellow Mentor.
Current Position: Medical Liaison, Immunology, Roche Pharmaceuticals
2007-2008 Isaac Bernstein-Hanley, PhD, Postdoctoral Fellow Mentor,
Current Position: Harvard School of Medicine, Research Liaison
2005-2008 Sarah Kennedy, PhD advisor/Postdoctoral Fellow Mentor.
Current Position: Medical Science Liaison, Immunology, UCB Pharmaceuticals
2005-2014 Ben Greenwood, Postdoctoral Fellow Mentor
Current Position: Assistant Professor, Depart of Psychology, University of Colorado at Denver
2011-2013 Peter Clark, PhD, Postdoctoral Mentor
Current Position: Assistant Professor, Iowa State University
2013-2014 Lida Beninson, Postdoctoral Mentor
Current Position: National Academy of Sciences, Program Officer, Washington, DC.
2016-2018 Aggie Mika, Postdoctoral Mentor
Current Position: Medical Associate, Health Care Consultancy Group, NY, NY.
Predoctoral Level Trainees: Current
2019-present Trey Jouard, Graduate Student Mentor
Postdoctoral Level Trainees: Current
2018-present Heidi Grabenstatter, Postdoc/Research Associate Advisor
2013-present Robert Thompson, Postdoctoral Advisor
Junior Faculty Supervised: Past and Present
2010-present Monique LeBourgeois, PhD-Assosciate Professor, IPHY
2004-present Marissa Ehringer, PhD-Associate Professor, IPHY & The Institute of
Behavioral Genetics
2003-2015 Kenneth Wright, PhD-Professor, IPHY & The Center for Neuroscience
2-Jul-19 42
Undergraduate Student Researchers Supervised: Past and Present
1998 Karianne Higgins, “Tissue catecholamines”, Hughes Undergraduate Research
Assistant Program (URAP)
1998 Ted Leem, “Bacterial inflammation”, Honor’s student
1999 Mary Nickerson, “Brain c-fos activity”, Undergraduate Research Opportunity
Program (UROP)
1999 Jason McCarl, “Total immunoglobulin”, UROP
2000 Kate Robinson,”Stress and catecholamines”, Independent study
2000 Kristine Thompson, “Celiac ganglion cfos”, UROP
2000 Deric McIntosh, “Autonomic brain nuclei and cfos”, UROP
2001 Heather Crump, “Stress and inflammation”, UROP
2001 Silvie Kilworth, “Stress and innate immunity”, Independent study
2001 Danielle Frey, “Cytokines and aging”, Independent study
2001 Julianna West, “Cell Localization of Intracellular HSP”, UROP
2001 Alexander Tran, “Splenic Sympathetic Content”, URAP
2001 Stephanie Cho, “Extracellular HSP and inflammation”, URAP
2001 Lisa Umphrey, “Exercise and brain cfos”, URAP
2001 Teresa Foley, “nIgM and Exercise”, URAP
2001 Deric McIntosh, “Neural basis of frustration”, Independent study
2002-2003 Daniel Burhans, “Exercise and BNST”, UROP, Work study
2002-2003 Melissa Hippley, “nIgM and Exercise”, Independent study/URAP
2002-2003 Leah Brooks, “Neurochemistry of exercise”, Independent study
2002 Karen Tal Oren, “Exercise and aging”, Independent study
2002 Probin Shrestha, Volunteer medical aid - Kanti Children’s Hospital Nepal,
Independent study
2002 Lindsay Levkoff, “Exercise and nIgM”, URAP
2002 Peter Bekker, “Aging and the antibody response”, Volunteer
2002 Heather Crump, “Brain responses to bacteria and prior stress”, UROP
2003 Brittany Shock, “Stress and splenic NE”, URAP
2003 Katherine Hooley, “E. coli and brain IL1”, URAP
2003 Craig Sharkey, “Stress and bacterial inflammation”, URAP
2003 Carla Amat, “5HT1A and exercise”, Independent study
2003 Lisa Malloy, “SERT and stress”, Independent study
2004 James Lish, “BK vascular leaking and Hsp72”, Independent study
2004 Jeff Kimes, “Hsp72 in brain and spleen”, Independent study
2004 Ashley Eyre, “Stress and brain Hsp72”, Independent study
2005 Garth Huberty, “EAE and neuroinflammatory pain”, Independent study
2005 Robert Thompson, “Neural mechanism of the protective effects of exercise on
stress-induced affective disregulation”, Independent study
2005-2006 Paul Strong, UROP, Independent study
2005-2007 Kristen Hetzler, “Heat shock proteins and stress”, Independent study
2005-2007 Hugo (Trey) Hanson, “IL1 and the brain”, Work study
2006 Valerie Cortez, SMART student, “NE and brain IL1”
2006-2007 Sarah Naguse, UROP
2006 Delsa Phillips, Independent study sponsor for Global Service Corp
2006-2008 Janelle Posey, “Brain Hsps”, NIMH minority undergraduate trainee
2008 Lydia Urrutia, “Brain and 5HT”, UROP
2006-2009 Sam Bowers, “Bacteria, brain and stress”, High School Student Worker
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2008-2009 Bradley Frazier, “Stress, 5HT and behavior”, UROP
2008-2009 Brianne Loughridge, “Stress, 5HT and behavior”, UROP
2008-2009 Tony Le, “Exercise and Motivation”, Independent study
2008-2009 Katharine Strelitz, “Stress, 5HT and behavior”, Independent study
2008-2009 Julia Rennick, “Stress and vascular cytokintes”, Independent study
2009-2011 Arman Serebrakian, “Stress & Adipose”, Independent study
2009-2011 Danielle Crevling, HHMI, Independent study, “Stress, 5HT and behavior”
2009-2011 Justin Hellwinkel, “Stress, 5HT and behavior”, Independent study
2010 Sierra Wohlman, “Stress and immunity”, Independent study
2010-2011 Wendy Craig, “Stress and cardiovascular adaptations”, Independent study
2010-2012 Katie Spence, “Stress, 5HT and behavior”, Independent study
2010-2012 Lucas Macaffey, “Stress and Immunity”, Independent study, UROP
2010-2012 Kate Tannura, “Stress and immunity” Independent study, UROP
2010-2012 Noaura Sadaoui, Work study, NIH HHMI, “Gene array analyses of DRN”
2010-2012 Stewart Cox, Independent study
2011 Phillip Adams, “Gene array analyses of DRN”, Work study
2011 Charlie Bowers, High School Student Worker
2011 Leslie Blacksheer, “Stress, fat and cytokines”, Volunteer
2011-present Jonathan Herra, “Stress, fat and cytokines”, Independent study
2011-2012 Jodie Rigali, “Stress, 5HT and behavior”, Independent study
2011-2012 Michael Murphy, “Hsp72 and releasing signals”, Independent
study, BURST applicant
2011-2012 Abigail Hills, Independent study
2011 Brittany Sak, Internship
2011 Taylor Schmidt, Internship
2012-2014 Parsa Ghasem Independent study, Honor’s Thesis (HHMI awardee)
2012-2014 Samantha Engel Independent study (Honor’s student)
2013-2014 Courtney Bouchet, Independent study, HHMI applicant, Honor’s Thesis
2013-2014 Roxie Christ, Independent study (UROP awardee)
2013-2014 Michelle Keag, Independent study (HHMI fellow)
2013-2014 Tyler Wieman, Independent study (BURST awardee)
2013-2014 Erika Sisneros (HHMI fellow)
2013-2014 Haley Manchester (BURST awardee)
2013-2014 Preston Bunker (HHMI awardee)
2013-2014 Sara McConnell (UROP awardee)
2013-2014 Tyler Woodworth (UROP, Independent Study)
2014 James Needle (RA)
2014 Nicco Baumann (Independent Study)
2013-2016 Kristina Hulen (HHMI awardee RA)
2013-2015 Donald Borchert (HHMI fellow, Independent Study)
2013-2016 Nicole Rumian (Independent Study, HHMI Awardee)
2014-2015 Mira Guha (Monarch High School, Science Research Seminar Program)
2014-2017 Alex Martinez (RA)
2014-2016 Michelle Gaffney (BURST Awardee & HHMI Awardee)
2014-2016 Rachel Roller (BURST Awardee & HHMI Awardee, Honors Awardee)
2015-2017 Kevin O’Connor (BURST Awardee)
2016-2017 Monica Patten (BUST Awardee)
2016-2017 Shelby Hopkins (BURST Awardee, BSI Awardee, RA)
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2016-2018 Brooke Bower (BSI Awardee, Honors Awardee)
2016-2018 Leah Ramey (BSI Awardee)
2016-2019 Tel Kelley (Work Study, BSI Awardee)
2017-2019 Trey Jouard (Independent Study, Honors) 

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